摘要
目的：为了解流感裂解疫苗免疫效果及安全性。方法：2006年12月-2007年1月对建湖县279名健康人进行疫苗接种前后免疫水平观察。结果：接种疫苗后，流感病毒H1N1、H3N2、B（亚）型的HI抗体阳性率分别为96.1%、86.7%和97.1%，H1N1、H3N2、B（亚）型的HI抗体GMT增长倍数分别为933倍、259倍和495倍，抗体保护率分别为100%、98.9%、96.4%，3个型别之间阳性率、GMT增长倍数、保护率差异有显著的统计学意义。结论：证实流感裂解疫苗具有良好的免疫效果，值得进一步推广应用。
Objective ：To observe the immune effect and safety of split Flu vaccine. Methods：A total of 279 healthy people in Jianhu county were vaccinated from Dec 2006 to Jan 2007, their immunity level was evaluated before and after vaccination. Results：Mter immunization, the anti -HI seroconversion rates of H1N1 strain, H3N2 strain, B strain were 96. 1%, 86. 7% and 97. 1%, respectively. The anti - HI GMT of H1N1 strain, H3N2 strain, B strain were increased for 933,259,495 folds, respectively. The anti- HI seroprotected rates of H1N1 strain, H3N2 strain, B strain were 100% ,98. 9% ,96.4%, respectively. The statistical difference was found the anti - HI seroconversion rates, GMT, seroprotected rates among the 3 strains. Condusion：Spht flu vaccine is worthy of popularization for its good immune effect and safety.
出处
《中国卫生检验杂志》
CAS
2008年第3期510-511,共2页
Chinese Journal of Health Laboratory Technology
关键词
流感裂解疫苗
免疫效果
安全性
Split- virus flu vaccine
Immune effect
Safety
作者简介
吴巨飞（1976-），学士，主管技师，主要从事微生物检验工作。
