摘要
帕金森病是中老年人常见的中枢神经系统变性疾病。星形胶质细胞可能参与了其发病过程,一方面,它可以通过释放神经营养因子、谷胱甘肽等保护多巴胺能神经元,在帕金森病中发挥保护作用;另一方面,它也可能通过释放一些促炎症因子而推动帕金森病的发生和发展。
Parkinson＇ s disease（PD） is a progressive neurodegenerative disorder harming mainly the elderly. Astrocyte may be involved in the pathogenesis of PD. However, it also plays a protective role in PD by releasing neurotrophic factors and glutathione to support the survival of dopaminergic neurons. Astrocyte may also release proin-flammatory cytokines to promote the development of PD.
出处
《基础医学与临床》
CSCD
北大核心
2008年第5期516-518,共3页
Basic and Clinical Medicine
基金
北京市留学人员科技活动择优资助项目(2007)
北京市科技计划课题(Z0005187040311)
作者简介
通信作者（corresponding author）：13718017202；yongmeizhao@hotmail．com
