摘要
目的:筛选对脑脉通颗粒中有效成分吸附和解吸最佳的大孔吸附树脂。方法:采用紫外分光光度法和高效液相色谱法测定不同大孔吸附树脂对指标性成分总蒽醌、总皂苷、总生物碱和葛根素的吸附和解吸率。结果:各指标性成分在不同型号大孔吸附树脂上的吸附和解吸率有差异。综合各树脂对各指标性成分的吸附性可知,AB-8型大孔吸附树脂对脑脉通颗粒有较好的纯化效果。结论:本研究结果可为实际生产提供理论依据。
OBJECTIVE： To optimize the macroporous absorbing resin which were of best action in adsorption and desorption on the active components in Naomaitong granules. METHODS： UV spectrophotometry and HPLC was employed to determine the adsorbability and desorption capacity of different macroporous absorbing resins on total anthraquinones, total ginsenosides, total alkaloids and Puerarin. RESULTS： There were differences in adsorption and desorption capacity on active components in Naomaitong granules among different macroporous absorbing resins. Considering the general adsorbability and desorption capacity of different macroporous absorbing resins, AB - 8 turned out to be of the best purification effect on Naomaitong granules. CONCLUSION： The results serve as a theoretical basis for the production of Naomaitong granules.
出处
《中国药房》
CAS
CSCD
北大核心
2008年第15期1144-1146,共3页
China Pharmacy
基金
国家自然科学基金资助项目(30371812)
关键词
脑脉通颗粒
大孔吸附树脂
吸附
解吸附
有效成分
Naomaitong granules
Macroporous absorbing resin
Adsorption
Desorption
Active components
作者简介
副教授，博士，硕士研究生导师。研究方向：中药质量标准及新药开发。E-mail：shmwang@sina.com
通讯作者：教授。研究方向：中药质量控制。电话：020—39352172。E-mail：swliang371@163．com
