摘要
目的：探讨兔VX2肾肿瘤超声造影的图像特征。方法：12只新西兰兔采用包埋法于右肾植入VX2肿瘤,共12个结节。经外周静脉注射声诺维（SonoVue）,分别于植瘤后7、14、21 d进行超声造影,观察VX2肿瘤大小及其灌注特点。结果：肿瘤最佳干预时间为植入后2-3周,3周后易发生坏死。VX2肾肿瘤超声造影后主要表现为充盈缺损的＂负显影＂,可使肾肿瘤的检出率由造影前的57.1%（12/21）提高至造影后的100%（21/21）。结论：超声造影可明显加强肿瘤血流信号的显示,显著提高VX2肾肿瘤的诊断率。
Objective：To evaluate the characteristics of contrast-enhanced ultrasonography in renal VX2 tumors. Methods： VX2 tumors were transplanted into 12 rabbit kidneys and observations were made by contrast-enhanced ultrasonography 7,14 and 21 days after the transplantation respectively. Results： The best intervention time was 2 -3 weeks after the tumor transplantation,while nicrosis was apt to occur after 3 weeks. The visibility of the renal tumors was significantly increased from 57. 1% （ 12/21 ） to 100% （21/21）. Contrast-enhanced uhrasonography showed defect and delineation of VX2 tumors. Conclusion： Contrast-enhanced uhrasonography can improve the peripheral and internal blood flows of the tumors promote the diagnosis of renal tumors.
出处
《医学研究生学报》
CAS
2008年第5期491-493,I0005,共4页
Journal of Medical Postgraduates
基金
南京军区南京总医院科研基金重点资助项目(批准号:2005115)
关键词
超声造影
肾肿瘤
VX2
Contrast-enhanced uhrasonography
Renal tumor
VX2
作者简介
沈德娟（1979-），女，江苏江都人，医学硕士研究生，从事超声诊断专业。
通讯作者：杨斌（1959-），男，江苏无锡人，主任医师，医学博士，从事超声诊断专业。
