摘要
目的评价冠状动脉钙化积分(CCS)为0者,多层螺旋CT(MSCT)检出冠状动脉非钙化斑块的意义及与冠心病危险因素的关系。方法132例病人进行16层CT冠状动脉钙化积分检查,其中52例病人CCS为0,进一步行冠状动脉多层螺旋CT血管造影(MSCTA)检查,确定非钙化斑块的存在,并分析非钙化斑块与冠心病危险因素(年龄、性别、高血脂、高血压、吸烟、糖尿病及冠心病家族史)的关系。结果52例CCS为0病人,35例发现非钙化斑块,共66块,28例确诊为冠心病。Logistic回归分析显示非钙化斑块的存在与冠心病危险因素中的高血脂、吸烟有关(P<0.05)。结论采用MSCT冠状动脉钙化积分检查评价冠心病风险的病人,若CCS为0且有高血脂和/或吸烟者的被检者,应进一步进行冠状动脉MSCTA检查,明确有无非钙化斑块的存在。
Objective To investigate the relationship between the non- calcified coronary plaques and the risk factors of coronary heart disease （CHD）. Methods Coronary calcium scores （CCS） were calculated with a multislice spiral CT （MSCT） scanner in 132 patients （pts） and MSCT angiography （MSCTA） was performed in 52 pts with CCS zero. The relationship between the non- calcified coronary plaques and the risk factors of CHD （age, gender, hypertension, hypercholesterolemia, diabetes, smoking, positive family history of CHD） were assessed. Results There were 66 non - calcified coronary plaques in 35 of 52 pts with CCS zero and 28 of 35 pts were diagnosed as CHD. Non - calcified coronary plaques were related with hypercholesterolernia, smoking. Conclusion CCS with MSCT could be used to determine the risk of CHD. Coronary artery MSCTA should be performed for pts with zero of CCS and with hypercholesterolemia and smoking to determine the non - calcified coronary plaques.
出处
《中西医结合心脑血管病杂志》
2008年第5期525-527,共3页
Chinese Journal of Integrative Medicine on Cardio-Cerebrovascular Disease
基金
珠海市科学技术局基金资助项目(No.PC20041038)
关键词
冠状动脉疾病
非钙化斑块
CT血管造影
危险因素
coronary artery disease
noncalcified plaques
Computed tomographic angiography
risk factor
作者简介
王颖（1968-），女，副主任医师，硕士，现工作于中山大学附属第五医院（邮编：519000）
通讯作者
