摘要
目的探讨神经元移行异常的影像学特征,提高对其认识能力和诊断水平。方法回顾性分析32例临床影像学资料完整的病例,脑裂畸形16例,灰质异位10例,无脑回或巨脑回畸形6例;主要临床表现为智力低下、癫痫和偏瘫等;结果脑裂畸形特征由灰质相衬的裂隙横跨半球,内达侧脑室,所衬灰质与大脑皮层连续,影像与灰质等密度;灰质异位CT和MRI表现为皮质下白质区.侧脑室室管膜下结节状、团块状或带状病灶,在所有序列上与正常脑灰质信号相同;无脑回\巨脑回畸形脑表面光滑或部分区域光滑、平坦,脑回、脑沟消失,脑皮层增厚。结论头颅CT和MRI是显示神经元移行异常最佳检查方法。
Objective To explore the imaging characteristics of neuronal migration anomalies in order to improve the diagnostic ability of it. Methods A retrospective study of 32 patients diagnosed as Neuronal Migration Anomalies was conducted. 16 of them were schizencephaly, 10 gray matter heterotopia, and 6 were lissencephaly or pachygyria. The main clinical manifestations of them are mental retardation, epilepsy and hemiplegia, etc. Results The characteristic appearance of schizencephaly was that the full-thickness cleft extended from the ventricle to the surface of the brain and was lined with gray matter, that lined gray matter was isodensity on computerized tomography （CT） and continuous with adjacent cerebral cortices; cranial CT and magnetic resonance imaging （MRI） showed heterotopic gray matter in the subcortical white region. The nodules and bolus or band heterotopia in subependymal of lateral ventricle had a signal intensity that was similar to that of the gray matter on each sequence in MRI. The surface of the brain diagnosed pachygyria or agyria remained flat and smooth; cerebral gyri and sulci disappeared; the cortex was thickened. Conclusion CT and MRI are the excellent way to display the features of neuronal migration anomalies.
出处
《罕少疾病杂志》
2008年第2期12-14,共3页
Journal of Rare and Uncommon Diseases
