摘要
目的:探讨光敏化姜黄素对人乳腺癌MCF-7细胞的抑制作用。方法:应用MTT法检测不同浓度和光照时间的姜黄素对人乳腺癌MCF-7细胞生长的影响。结果:光敏化姜黄素对人乳腺癌MCF-7细胞的生长起抑制和杀伤作用,并且这种作用随着姜黄素浓度的增加和光照时间的延长而增强。结论:姜黄素是一种新型的光敏剂,能有效的杀伤和抑制人乳腺癌MCF-7细胞的生长。
Objective：The aim of the present study is to explore the inhibitive action of photoactive eurcumin on human breast cancer cells. Methods： MTT reduction assay was performed to measure the photoinactivation of MCF - 7 cells with the different concentrations of curcumin. Results： Photoacfive curcumin could significantly inhibit the growth of human breast cancer MCF - 7 cells along with the increasing of carcumin concentrations and the prolong of irradiation time. Conclusion： Curcumin is a new photosensitizer which could effectively inhibit the growth of human cancer of MCF - 7 cells.
出处
《激光杂志》
CAS
CSCD
北大核心
2008年第2期81-82,共2页
Laser Journal
基金
国家高新技术研究发展规划项目(863计划)资助(2006AA02Z4F0)
关键词
乳腺癌
姜黄素
光动力治疗
breast cancer
curcumin
photodynamic therapy
作者简介
通讯作者：许川山
