摘要
广州管圆线虫病是严重危害人类健康的人兽共患寄生虫病之一,主要表现为中枢神经系统病变,严重者可造成死亡。该病临床症状复杂多样,极易误诊,因此早期、及时的明确诊断是该病预防与治疗的首要条件。国内外许多研究者为寻找快速、早期、准确的诊断方法,对已成熟且普遍使用的ELISA检测方法进行了多种优化研究。衡量ELISA检测可靠性的关键是敏感性高、特异性强的抗原、抗体。该文将广州管圆线虫特异性抗原、抗体的优化研究作一综述,为广州管圆线虫病的免疫诊断提供一定的参考价值。
Angiostrongyliasis eantonensis is one of parasitic zoonoses that severely affect human health, characterized by the pathological process of central nervous system. Severe eases may lead to death. Clinical manifestion is complex, which easily leads to misdiagnosis. Therefore, the most important requirement for prevention and treatment is to make a prompt and correct diagnosis. In order to search early, rapid and accurate diagnostic methods, many scholars optimized the detection of ELISA from many aspects. This review is about the research progress on specific, sensitive antigen and antibody to angiostrongyliasis eantonensis.
出处
《国际医学寄生虫病杂志》
CAS
2008年第1期41-45,共5页
International JOurnal of Medical Parasitic Diseases
基金
基金项目:广州市科技局基金(2005Z3-c7561
2006Z3-c7191)
国家自然科学基金一广东省人民政府联合基金(U632003)
关键词
广州管圆线虫病
免疫诊断
特异性抗原
特异性抗体
Angiostrongyliasis eantonensis
Immunodiagnosis
Specific antigen
Specific antibody
作者简介
通讯作者:詹希美,Email:zhanximei@yahoo.com.cn