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泌尿生殖系标本支原体培养及药敏分析 被引量:26

Mycoplasma culture and the analysis of drug susceptibility of genitourinary specimens
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摘要 目的了解某院泌尿生殖系感染患者的支原体感染及药敏情况,为临床合理治疗提供依据。方法采用板条培养药敏试剂法对所取标本进行解脲支原体(Uu)和人型支原体(Mh)检测,并对阳性标本进行11种抗菌药物的药敏测定。结果共检测1048份送检标本,支原体总阳性率为38.26%(401/1048),其中单一Uu感染302例,单一Mh感染19例,Uu合并Mh感染80例。女性支原体阳性检出率为42.78%,男性为29.49%,前者显著高于后者(χ2=13.618,P<0.01)。支原体对交沙霉素、美满霉素、多西环素敏感率较高,分别为99.25%、98.00%、97.51%;对环丙沙星的敏感率最低,为16.21%。结论泌尿生殖系支原体感染主要以Uu为主,应重视培养、鉴定及药敏结果,以合理选择敏感药物进行治疗。 Objective To realize Mycoplasma infection and the drug susceptibility in patients with genitourinary tract infection in a hospital so as to provide guidance for rational clinical treatment. Methods Ureaplasma urealyticum (Uu)and Mycoplasma hominis (Mh)were detected with lath culture sensitivity reagent method, and drug susceptibility test results were analyzed with 11 kinds of antimicrobial agents. Results 1 048 specimens were detected, the total positive rate of Mycoplasma was 38. 26% (401/1 048), 302 cases were only Uu infection and 19 cases were only Mh infection, 80 cases were both Uu and Mh infections. The positive rate in female and male was 42. 78% and 29. 49 % respectively, the infection rate of female was obviously higher than that of male(χ^2 = 13. 618, P〈0. 01). The drug-resistant rates of Mycoplasma to josamycin, doxycycline and minocycline were high, which was 99. 25 %, 98. 00% and 97. 51% respectively; The drug-resistant rate to ciprofloxacin was the lowest, which was 16. 21%. Conclusion The main pathogen of the Mycoplasma infection was Uu in patients with genitourinary tract infection. the culture, identification and drug susceptibility test results should be paid attention, susceptible agents should be chosen rationally for treatment.
出处 《中国感染控制杂志》 CAS 2008年第1期46-48,共3页 Chinese Journal of Infection Control
关键词 泌尿生殖系感染 解脲支原体 人型支原体 微生物敏感性试验 抗药性 微生物 genitourinary infection Ureaplasma urealyticum Mycoplasma hominis antimicrobial susceptibility test drug resistance, microbial
作者简介 陈利(1964-),女(汉族),湖南省益阳市人,副主任检验师,主要从事临床检验研究。[通讯作者]陈利 E-mail:Chen Li-11@hotmail.com
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