摘要
目的探讨子痫前期合并心衰的治疗要点及预防措施。方法选择2001年1月～2006年6月间收治的子痫前期患者108例，其中合并心衰者43例，随机分为硝酸甘油治疗组（A组）和硫酸镁治疗组（B组），分别检测治疗前、后的血压、心率及血细胞压积。结果两组用药前、后平均血压及心率分别由17．02±0，40kPa、123±3．1次／分降为13．03±0．47kPa、92±2．5次／分，硝酸甘油治疗组明显优于硫酸镁治疗组，差异有统计学意义（P〈0．05）。结论定期产前检查、重视诱因、迅速控制血压是预防心衰的关键，硝酸甘油治疗子痫前期合并心衰安全且效果显著，在保障母婴安全和降低围产期孕产妇及围生儿的死亡率方面有重要的作用。
Objective To explore treatment points and preventions of pre-eclampsia associated with heart failure. Methods 108 pregnant women with pre-eclampsia admitted to and treated in our hospital from January 2001 to June 2006 were selected. Of which, 43 pregnant women with pre-eclampsia were associated with heart failure and they were divided randomly into nitroglycerin treatment group （group A） and magnesium sulfate treatment group （group B）. Blood pressure, heart rate and bepacked cell volume of the pregnant women with pre-eclampsia associated with heart failure in the two groups were examined before and after treatment. Results Mean arterial blood pressure and heart rate before and after administration of the two drugs in the two groups dropped from 17.02 ± 0.40kPa, 123 ± 3.1 beats per minute to 13.03 ± 0.47kPa, 92 ± 2.5 beats per minute respectively and the differences were significant （ both P 〈 0.05 ）. Conclusion Regular prenatal examination, paying attention to the incentives and rapid blood pressure control are the key to prevent heart failure. Nitroglycerin can safely and effectively treat heart failure in pre-eclampsia, and the therapeutic effect is significant. Nitroglycerin plays an important role in protecting maternal and infanile safety and in reducing the maternal and neonatal mortality.
出处
《中国妇幼健康研究》
2008年第1期39-40,共2页
Chinese Journal of Woman and Child Health Research
关键词
妊娠子痫前期
心衰
硝酸甘油
治疗
pre-eclampsia
heart failure
nitroglycerin
treatment
作者简介
刘晓丽（1965-），女，副主任医师，主要从事孕产妇急危重症急救工作。
