摘要
其常见病因及临床特点。方法:对2003-07/2007-05就诊于我院门诊的1220例浅层点状角膜炎的病例行裂隙灯检查,角膜染色检查,泪膜破裂时间(<10s为阳性),泪河宽度(<0.5mm为阳性),SchirmerⅠ试验及刮片细菌培养。之后按其病因,性别,眼别进行了分类统计。结果:1220例浅层点状角膜炎的病例中,男460例(920眼),女760例(1520眼),男与女比为1∶1.65。单眼发病408例,双眼发病812例,两者比例近1∶2。原因不明的干眼症所致角膜炎为277例(22.7%)。其次是各种原因所致的暴露性角膜炎229例(18.8%)。再次为倒睫致角膜炎,角膜接触镜所致角膜炎,眼表不规则,化妆品所致角膜炎等。结论:统计结果揭示女性及双眼发病较为常见。不明原因干眼症所致角膜炎日趋增多,应引起足够重视,且绝大多数浅层点状角膜炎都是有因可查,病因不明者仅占极少数。其中感染性原因明显减少,非感染性原因则显著增多,提示在临床工作中要注意非感染因素的存在及严重危害,并做到对症治疗。
AIM： Through the statistical analysis of superficial punctate keratitis in out-patients, to reveal its common causes and clinical characteristics. METHODS： A total of 1 220 cases with superficial punctate keratitis who attended the clinic from July 2003 to May 2007 in our hospital were systematically reviewed. All cases underwent slit-lamp examination, corneal staining, tear film break-up time （〈10 seconds is positive）, lacrimal river width （〈0.5 mm is positive）, Schirmer I test and bacterial culture. Then their causes, sex, and affected eyes were classified and statistical analysis was carried out.RESULTS：Among the 1 220 cases, 460 cases were male （920 eyes）, while 760 cases were female （1 520 eyes）. The ratio of male to female is 1：1.65. 408 cases had monocular incidence, and 812 cases had binocular incidence. The ratio between them is 1： 2. Unexplained keratitis caused by dry eye occurred in 277 cases （22.7%）. Second, the exposure keratitis due to various reasons occurred in 229 cases （18. 7%）. Trichiasis keratitis, keratitis caused by contact lens, keratitis caused by cosmetics and ocular surface irregularity came last. CONCLUSION： The statistical results revealed that women and binocular incidence are more common. The incidence of keratitis caused by dry eye disease of unknown reasons is growing, so we should pay sufficient attention. Moreover, the causes of a vast majority of su-perficial punctate keratitis can be found by investigation. Only a handful of cases had unknown causes. Infectious causes decreased significantly, while non-infectious causes markedly increased, suggesting that in clinical work, we should pay attention to existence and serious hazards of non-infectious factors to implement symptomatic treatment.
出处
《国际眼科杂志》
CAS
2008年第1期171-174,共4页
International Eye Science
基金
中国广东省科学技术研究基金资助(No.B2006118)~~
关键词
浅层点状角膜炎
临床特点
门诊
病因
superficial punctate keratitis
clinical characteristics
作者简介
通讯作者：刘琳，女，主治医师。jiangqiangliulin@126．com
