摘要
为了观察盐酸多西环素对急性期犬埃立克体病的治疗效果,对人工感染埃立克体的比格犬进行了盐酸多西环素的治疗试验。采集比格犬感染前及治疗前后的血液样本,测定血常规及各项血生化指标,并对测定结果作统计学处理。血常规检测发现与治疗前相比,治疗后RBC、WBC、HGB、PLT、MPV、NEU-TRO、LYM、MONO和RDW显著升高;HCT、MCV、MCH和MCHC无明显变化;血生化检测发现,与治疗前相比,治疗后ALT和AST显著降低,ALB显著升高;治疗后与感染前相比,血常规和血生化各项均没有显著变化。进一步证实了盐酸多西环素对犬埃立克体病急性期病例具有良好的治疗效果。
To study therapeutic efficacy of Doxycycline Hyclate, beagle dogs infected artificially with Ehrlichia Canis and E. platys were treated. Blood samples were obtained and analysed from 6 Beagle dogs before infection, after infection and after treatment. Comparing between before-treament and after-treatment, RBC, WBC, HGB, PLT, MPV, NEUTRO, LYM, MONO, RDW and ALB increased significantly, ALT and AST decreased significantly; comparing between before-infection and after-treatment, there were no significant changes in all blood routine and biochemical indexes. Our research confirmed that doxycycline hyclute can cure dogs with acute canine ehrlichiosis .
出处
《动物医学进展》
CSCD
2008年第1期28-31,共4页
Progress In Veterinary Medicine
基金
总后勤部面上课题(01MB035)
广东省科技计划项目(2005B60302007)
关键词
埃立克体病
盐酸多西环素
血常规
血生化指标
比格犬
ehrlichiosis
doxycycline hyclate
blood routine
blood biochemical indexes
Beagle dog
作者简介
马玉海（1966-），男，吉林四平人,副研究员，主要从事犬传染病研究
通讯作者
