摘要
以变应性鼻炎小鼠为模型,采用均匀设计法,探讨加味麻黄附子细辛汤组方合理性及配比剂量。结果各药物在鼻敏康组方中的重要性地位依次为:附子>黄芪>防风>麻黄>细辛>白术;附子、黄芪、防风、细辛的用量与疗效呈正相关,即用量较大时疗效较好;麻黄、白术的用量与疗效呈负相关,即用量较少时疗效较好;麻黄与细辛、黄芪与附子间的交互作用呈正相关;麻黄与黄芪、黄芪与白术间的交互作用呈负相关,组方时应适当增加或减少相关药物的用量。
Using ethology of average incidence of allergic rhinitis mice C57BL6 as index,uniform design is adopted to optimize formula and dose of modified ephedra asarum herb aconite decoction, the sequence of importance is . aconite 〉 astragalus 〉 Saposhnikovia divaficata （Turez.） Schischk 〉 ephedra 〉 asarum herb 〉 atractyledes macrocephala; aconite, astragalus,Saposhnikovia divaricata （Turez.） Schischk,asarum herb have positive relationship with the number of grabbing nose, ephedra,atractyledes macrocephala have negetive relationship with the number of grabbing nose; the interaction of ephedra and asarum herb, astragalus and aconite are positive ;ephedra and astragalus, astragalus and Saposhnikovia divaricata （Turez.） Schischk are negative.
出处
《中华中医药学刊》
CAS
2008年第1期123-124,共2页
Chinese Archives of Traditional Chinese Medicine
基金
辽宁省科技厅资助项目(2004226010-1)
关键词
加味麻黄附子细辛汤
变应性鼻炎
均匀设计
modified ephedra asarum herb aconite decoction
allergic rhinitis
uniform design
作者简介
林瑞红（1969-），女，辽宁沈阳人，高级工程师，主要从事药品生产监督管理及药品检验工作。
