摘要
目的评价高危急性心肌梗死患者行急诊介入治疗术时常规主动脉内球囊反搏术(IABP)的可行性及其疗效。方法41例高危急性心肌梗死行急诊介入并主动脉内球囊反搏术治疗的患者,为治疗组(A组),将同期行急诊介入治疗但没有行主动脉内球囊反搏术治疗的高危心肌梗死患者配对入选38例设为对照组(B组)。比较两组术后30d内左室功能改善情况以及心肌缺血事件和心脏主要不良事件等的发生率。结果A组患者术后30d内左室功能较B组明显改善(P<0.05),心肌缺血事件的发生率A组较B组少(P<0.05),两组在死亡率、再次心肌梗死发生率和再次血运重建率等方面差别也有统计学意义(P<0.05)。结论对高危急性心肌梗死患者做紧急介入治疗术前常规进行IABP可以有效改善患者左室功能和心脏主要不良事件的发生率,但这一结果仍需大规模临床试验验证。
Objective To assess the value of routine intra-aortic balloon pump （IABP） support in patients with high-risk acute myocardial infarction （AMI） undergoing percutaneous coronary intervention （PCI）. Methods The clinical data of 41 patients with high-risk AMI undergoing emergency PCI with routine IABP support were retrospectively reviewed, and 38 patients paired with the former group receiving emergency PCI for high-risk AMI without IABP support at the same time were included as the control group. Thirty days after the operation, the two groups were compared for myocardial ischemic events, left ventricular function and major adverse cardiac events （MACE）. Results Patients receiving IABP support had a significantly lower incidence of myocardial ischemic events than those without IABP （4.9% vs 15.8%, P〈0.05）, and showed greater improvement in the left ventricular function. Significant differences were also observed in the mortality rate, incidence of reinfarction and revascularization rate between the two groups, but not in the rate of MACE. Conclusions Patients undergoing PCI for high-risk acute AMI can benefit from routine IABP support in terms of improvement of left ventricular function and reduce myocardial ischemic events and the rate of MACE. These results, however, still await further confirmation by large-scale clinical trials.
出处
《南方医科大学学报》
CAS
CSCD
北大核心
2007年第12期1927-1928,1931,共3页
Journal of Southern Medical University
关键词
心肌梗死
主动脉内球囊反搏术
左室功能
心脏主要不良事件
acute myocardial infarction
intra-aortic balloon pump
left ventricular function
major adverse cardiac events
作者简介
陈军（1962-），男，主任医师，E-mail：szchenjun@medmail．com．cn
