摘要
目的探讨过敏性紫癜(HSP)患儿肾损害早期诊断的实验室指标,为HSP患儿肾损害的早期诊断提供依据。方法选取45例血清C r正常HSP患儿作为观察组,30例健康儿童作为健康对照组。抽血后采用酶联免疫吸附法(ELISA)测定血清半胱氨酸蛋白酶抑制剂C(Cyst-C)。同时对观察组行尿常规检测。结果HSP组血清Cyst-C显著高于健康对照组(P<0.01),HSP患儿尿常规阳性率33.3%(15/45),而血清Cyst-C阳性率71.1%(35/45),二者间有统计学差异(P<0.01)。结论通过检测HSP患儿血清Cyst-C,有助于发现血C r正常的早期肾功能损害。
Objective To explore the diagnosis value of cystatin C （ Cyst - C） level on the renal function early impairment of Henoch - Schonlein parpura（HSP）. Methods The selected serum creatinine（SCr） normal 45 sufferers,with measured their urine routine analysis,and the same time did serum Cyst - C. Compared with 30 healthy children of serum Cyst - C. Results The levels of serum Cyst - C in HSP were definitely higher than these in healthy group ,and the differences were together with its signifincance （P 〈 0.01 ）, the positive detection rate of urine routine was 33.3% （ 15/45 ）, and the positive rate of serum Cyst - C was 71.7% （ 35/45 ）. There was statistical significance between 2 groups （P 〈 0.01 ）. Conclusion The positive is probably elevated in early stage of renal disfunction and can be used as a more senstive marker than creatinine.
出处
《实用儿科临床杂志》
CAS
CSCD
北大核心
2007年第21期1650-1651,共2页
Journal of Applied Clinical Pediatrics
作者简介
陆晓萍，女，主治医师，学士学位，研究方向为呼吸系统疾病。
