摘要
目的:比较老年高血压患者血尿酸水平与血压及颈动脉硬化程度的相关性。方法:将102例老年高血压患者按血压值的不同分为三组,比较各组间血尿酸与血压的相关性,对各例患者分别检测血生化指标:空腹血糖(FBG)、血尿酸(UA)、甘油三脂(TG)和总胆固醇(TC),B超观察颈动脉变化,按B超结果将患者分为内膜正常组、内膜增厚组、斑块形成组和管腔狭窄组,比较各组间血压、血尿酸水平。结果:三组高血压患者血尿酸值分别为(318±35)、(366±37)、(426±52)μmol/L,各组间比较差异有显著性(P<0.01)。颈动脉内膜正常组血尿酸值为(269±51)μmol/L,内膜异常组血尿酸值依次为(318±38)、(366±46)、(429±51)μmol/L,各组间比较血尿酸值的差异有显著性(P<0.01)。结论:老年高血压患者颈动脉硬化程度与血压、血尿酸水平呈正相关。提示高尿酸血症是高血压病的危险因素之一,高尿酸血症与高血压是心血管疾病的重要易感因素。
Objective： To compare the relationship among the level of serum uric acid hypertension and carotid atherosclerosis in elderly patients with hypertension, Methods：To divide 102 patients with elderly hypertensive into 3 groups according to the difference of blood pressure resuh,and Compare the relationship between serum uric acid and blood pressure among the different groups,They were divided into normal group,intimae tricking group,plaque shaping group and vascular stenosis group accoraing to ultrasound result. To compare the serum uric acid level and blood pressure among each group. Results：Uric acid results in the 3 hypertensive groups were （318±35）, （366±37）, （426± 52） μmol/L. There were statistical meaning to compare differences among groups（P〈0.01 ）. Uric acid in the carotid artery normal group was （269!51） μmol/L,the other three carotid artery abnormal groups were （318±38）, （366±46）, （429±51 ）μmol/L. To compare uric acid difference among each group, there were statistical meaning（P〈0. 01 ）. Conclusions：Carotid atherosclerosis of elderly patients with hypertensive is both correlated with the level of uric acid and blood pressure. It shows that high serum uric acid is one of the risk of hypertension and high serum uric acid and hypertension are main factors of cardiovascular disease.
出处
《中国误诊学杂志》
CAS
2007年第25期5957-5958,共2页
Chinese Journal of Misdiagnostics
基金
河北省科技厅2005年度科研项目(编号:052761824)
作者简介
刘爱学（1960-），女，河北怀委人，蓟主任医师。面巍方向：老年高血压、血尿酸和颈动脉硬化的相互关系。
