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可控制性卵巢刺激治疗中促性腺激素释放激素激动剂降调节与卵巢过度抑制 被引量:24

Ovarian poor responder correlated with GnRH-a down regulation
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摘要 The retrospective study showed that 87.4%(248/279) ovarian poor responder could be reversed by reduced the dose of GnRH-a or increased initial Gn dose compared with full or a half dose and one third dose of GnRH-a down-regulation groups,only 11.1%(31/279) cases taken place ovarian poor responder again in next IVF-ET cycle.The result implied that profound ovarian suppression could be reversed by reduced GnRH-a dose or increased Gn dose in women with ovarian normal function.The dose of GnRH-a may have an impact on the steroidgenesis in IVF-ET cycles. The retrospective study showed that 87.4% (248/279) ovarian poor responder could be reversed by reduced the dose of GnRH-a or increased initial Gn dose compared with full or a half dose and one third dose of GnRH-a down-regulation groups, only 11.1% (31/279) cases taken place ovarian poor responder again in next IVF-ET cycle. The result implied that profound ovarian suppression could be reversed by reduced GnRH-a dose or increased Gn dose in women with ovarian normal function. The dose of GnRH-a may have an impact on the steroidgenesis in IVF-ET cycles.
出处 《生殖医学杂志》 CAS 2007年第5期306-308,共3页 Journal of Reproductive Medicine
关键词 促性腺激素释放激素激动剂 卵巢低反应 类固醇生成 GnRH-a Ovarian poor responder Steroidgenesis
作者简介 李洁(1964-),女,山东人,博士,副教授.
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参考文献7

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二级参考文献6

  • 1Porter RN,Smith W,Craft IL,et al.Induction of ovulation for in-vitro fertilisation using buserelin and gonadotropins.Lancet,1984,2:1284-1285.
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