摘要
目的考察唐古特白刺果总黄酮对衰老模型小鼠氧化能力的影响。方法用D-半乳糖制备衰老模型小鼠,以酶标法测定小鼠血清和肝组织中MDA,SOD,GSH-PX指标的变化。结果白刺果中总黄酮能显著降低衰老小鼠血清和肝组织MDA水平,同时可提高SOD和GSH-PX活力水平。结论唐古特白刺果总黄酮具有抗氧化作用。
Objective To study the effect of anti - oxidative in subacute aging model mice with total flavonoids of Uighur medicine's Nitraria tangutorun Bobr. Methods The aged mice were induced by ip D( + ) - galactose for 8 weeks. Determined malondialdehyde (MDA) superoxide dismutase (SOD) , glutathione peroxidase (GSH -PX) in the mice's serum and Hepar with model 680 Microplate Spectrophotometer. Results Total flavonoids of Uighur medicines Nitraria tangutorun Bobr. not only had significant inhibition effect on MDA levels but also increased the ratio of SOD activity and GSH - PX activity. Conclusion The total flavonoids of Uighur medicine's Nitraria tangutorun Bobr. has good anti - oxidative effect.
出处
《时珍国医国药》
CAS
CSCD
北大核心
2007年第10期2438-2440,共3页
Lishizhen Medicine and Materia Medica Research
基金
新疆生产建设兵团医药专项基金(No.NKBO3SDXYY39XY)
关键词
唐古特白刺
总黄酮
抗氧化
Nitraria tangutorum Bobr
Total flavonoids
Anti - oxidative effect
作者简介
樊莲莲(1981-),女(汉族),安徽阜阳人,硕士学位,主要从事天然药物的活性成分的研究工作.
通讯作者简介:刘金荣(1954-),女(汉族),河南淮阳人,现任石河子大学教授,主要从事天然药物的活性成分的研究工作.