期刊文献+

维药白刺总黄酮对亚急性衰老模型小鼠抗氧化作用的研究 被引量:14

Research on the Anti-oxidative Effect of Total Flavonoids of Uighur Medicine's Nitraria tangutorun Bobr. in Subacute Aging Model Mice
在线阅读 下载PDF
导出
摘要 目的考察唐古特白刺果总黄酮对衰老模型小鼠氧化能力的影响。方法用D-半乳糖制备衰老模型小鼠,以酶标法测定小鼠血清和肝组织中MDA,SOD,GSH-PX指标的变化。结果白刺果中总黄酮能显著降低衰老小鼠血清和肝组织MDA水平,同时可提高SOD和GSH-PX活力水平。结论唐古特白刺果总黄酮具有抗氧化作用。 Objective To study the effect of anti - oxidative in subacute aging model mice with total flavonoids of Uighur medicine's Nitraria tangutorun Bobr. Methods The aged mice were induced by ip D( + ) - galactose for 8 weeks. Determined malondialdehyde (MDA) superoxide dismutase (SOD) , glutathione peroxidase (GSH -PX) in the mice's serum and Hepar with model 680 Microplate Spectrophotometer. Results Total flavonoids of Uighur medicines Nitraria tangutorun Bobr. not only had significant inhibition effect on MDA levels but also increased the ratio of SOD activity and GSH - PX activity. Conclusion The total flavonoids of Uighur medicine's Nitraria tangutorun Bobr. has good anti - oxidative effect.
出处 《时珍国医国药》 CAS CSCD 北大核心 2007年第10期2438-2440,共3页 Lishizhen Medicine and Materia Medica Research
基金 新疆生产建设兵团医药专项基金(No.NKBO3SDXYY39XY)
关键词 唐古特白刺 总黄酮 抗氧化 Nitraria tangutorum Bobr Total flavonoids Anti - oxidative effect
作者简介 樊莲莲(1981-),女(汉族),安徽阜阳人,硕士学位,主要从事天然药物的活性成分的研究工作. 通讯作者简介:刘金荣(1954-),女(汉族),河南淮阳人,现任石河子大学教授,主要从事天然药物的活性成分的研究工作.
  • 相关文献

参考文献17

二级参考文献70

  • 1张尔贤,俞丽君,周意琳,肖湘.Fe^(2+)诱发脂蛋白PUFA过氧化体系及对若干天然产物抗氧化作用的评价[J].生物化学与生物物理学报,1996,28(2):218-222. 被引量:129
  • 2杨钧国.冠状动脉粥样硬化的危险因素和商皿脂[A].见:毛焕成,扬心田.心脏病学[C].北京:人民卫生出版社,1995.919-931.
  • 3翁玉椿 王秀平 卢泳才 等.细胞和细胞膜过氧化脂质的微量测定[J].细胞生物学杂志,1985,7(3):142-142.
  • 4Miao MS.Experimental Animal and Technology (实验动物和动物实验技术)[M].Beijing: Chinese Traditional Medical Publishing House,1997.199-202.
  • 5[1]Storlien LH, Oakes ND, Pan DA, et al. Syndromes of insulin resistance in the rat. Inducement by diet and amelioration with benfluorex[J]. Diabetes, 1993, 42(3):457-462.
  • 6[2]Tritos NA, Mantzoros. Syndrome of severe insulin resistance[J]. J Clin Endocrinol Metab,1998, 83(11):3025-3032.
  • 7[3]Storlien LH, Pan DA, Kusunoki M, et al. Effects of benfluorex on in vivo patterns of insulin resistance induced by diets rich in fat or fructose[J].Diabetes Metab Rev, 1993, 9 (Suppl 1):65S-72S.
  • 8[4]Battilana P, Seematter G, Schneiter P, et al. Effects of free fatty acids on insulin sensitivity and hemodynamics during mental stress[J]. J Clin Endocrinol Metab, 2001,86(1):124-128.
  • 9[5]Roden M, Shulman GI. Applications of NMR spectroscopy to study muscle glycogen metabolism in man[J]. Annu Rev Med,1999,50(5):277-290.
  • 10[6]Bieger WP, Michel G, Barwich D,et al. Diminished insulin receptors on monocytes and erythrocytes in hypertriglyceridemia[J]. Metabolism,1984 ,33(11):982-987.

共引文献237

同被引文献240

引证文献14

二级引证文献150

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部