摘要
载药脂质体给药系统已成为国内外的研究热点。传统脂质体经修饰和改良后表现出良好的生物相容性,缓释性和靶向性。新型脂质体在经皮给药,肺部给药,脑部靶向治疗,基因治疗等方面的应用研究结果显示,集药物缓释、靶向于一体的具有良好生物安全性的脂质体给药系统具有很大发展潜力。本文综述了该领域中的最新研究进展。
The application of liposome as a drug deliver system has become research hot topic at home and abroad. The liposome appears good biocompatibility, slow-releasing potential and targeting property after chemical or physical modification and improvement. The applications of liposome in trans-dermal drug delivery system, pulmonary drug delivery system, brain targeted thereby and gene therapy indicated that liposome drug delivery system will has great development potential for its good biocompatibility, slow-releasing potential and targeting property. The latest advancement in liposome research was reviewed in this paper.
出处
《现代生物医学进展》
CAS
2007年第10期1597-1600,共4页
Progress in Modern Biomedicine
关键词
脂质体
药物载体
缓释
靶向
liposome
drug carrier
sustained drug release
targeting
作者简介
杨静，（1985-），男，2004级本科，生物医学工程专业，Email：yj19852005@163．com
通讯作者：周绍兵，（1972-），男，博士，教授，研究方向为生物医用高分子材料及药物控制释放等
