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微动对骨折端骨密度的影响 被引量:6

Effects of micromovement on the bone mineral density of the broken end of bone fractures
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摘要 目的:研究骨折端微动时应力对骨密度的影响。方法:60只新西兰大白兔随机分为微动组与固定组,每组30只。固定组术后使骨折端固定。微动组使外固定架中间杆有0.5mm的轴向移动,术后动物自由行走,依靠体重使外固定架产生微动。利用双能X线骨密度测量仪测定两组动物骨痂的骨密度。结果:术后14d时固定组、微动组骨密度为正常的10%左右,两组无显著差异。21、28d两组骨密度有明显上升,微动组与固定组比较差异有显著性意义(P<0.01)。42d时微动组骨密度高于正常水平。56d时微动组骨密度稍下降,但仍高于正常,固定组骨密度高于正常水平,两组无显著差异(P>0.05)。结论:微动可增强骨愈合时骨痂的骨密度。 Objective:To study the influence of micromovement on the bone mineral density of the broken end of bone fractures, Methods:Sixty rabbits were randomly divided into micromovement group and fixation group, There were 30 rabbits in each group. After operation, the broken ends of rabbits in fixation group were fixed. In micromovement group,0, 5 mm space was left on middle rod of the external fixator, the broken ends of fractures of the rabbits could move axilely depending on their body weight, The bone mineral density (BMD) was measured with dual-energy X-ray absorptionmetry, Resets:At the 14th day after operation,the BMD of the micromovement group and the fixation group was just 10% of the normal level,there was no significantl difference between the two groups(P 〈0, 05), The BMD of the two groups increased greatly at the 21th and 28th days, the BMD of the micromovement group was higher than that of fixation group (P 〈 0. 01 ). At the 42 day, the BMD of micromovement group was higher than the mormal level. At the 56th day,the BMD of the two groups were both higher than the normal level, but there was no significant difference between the micromovement group and the fixation group ( P 〉 0, 05 ). Conclusion:Micromovement could in crease the bone mineral density,
出处 《中国骨伤》 CAS 2007年第9期603-604,共2页 China Journal of Orthopaedics and Traumatology
关键词 骨折 骨密度 外固定器 骨折愈合 Fractures Bone density External fixators Fracture healing
作者简介 通讯作者:乔林 Tel:010-66343367 E-mail:qiaolindoc@sohu.com
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参考文献5

  • 1Marcy W,Mark S,Kelly G.Cyclic tensile strain and cyclic hydrostatic pressure differentially regulate expression of hypertropic markers in primary chondrocytes.Bone,2003,33:685-693.
  • 2Mizuno S,Tateischi T,Ushida T,et al.Hydrostatic fluid pressure enhances matrix synthesis and accumulation by bovine chondrocytes in three-dimensional culture.J Cell Physiol,2002,139:319-327.
  • 3Claes LE,Heigele CA,Neidlinger-Wilke C,et al.Effects of mechanical factors on the fracture healing process.Clin Orthop Relat Res,1998,355:132-147.
  • 4Claes LE,Heigele CA.Magnitudes of local stress and strain along bony surfaces predict the course and type of fracture healing.J Biomech,1999,32(3):255-266.
  • 5Sarmiento A,Mckellop HA,Llinas A,et al.Effect of loading and fracture motions on diaphyseal tibial fracture.J Orthop Res,1996,14:80-84.

同被引文献32

  • 1尹东,杨惠林,唐天驷,张亚峰.双能X线骨密度仪测定骨痂骨密度变化的实验研究[J].中国医学影像学杂志,2004,12(6):430-432. 被引量:12
  • 2林良才.《理瀹骈文》对中医外治法发展的贡献之分析与研究[J].中医外治杂志,2005,14(4):6-7. 被引量:27
  • 3李明,李开凡,徐荣明,校佰平,毛伟民,裘邯军.CT引导下经皮空心拉力螺钉固定治疗骶髂关节损伤[J].中国骨伤,2006,19(9):526-528. 被引量:9
  • 4万春友,金鸿宾,王敬博,姚辉,卢艳东.Ⅱ型浮膝损伤术后膝关节功能康复[J].中国骨伤,2006,19(9):537-539. 被引量:4
  • 5Marcy W, Mark S, Kelly G. Cyclic tensile strain and cyclic hydrostatic pressure differentially regulate expression of hypertropic markers in primary chondrocytes[J].Bone, 2003, 33:685 -693.
  • 6Schild C, Trueb B. Mechanical stress is required for high level expression of connective tissue growth factor[J]. Exp Cell Res, 2002, 274:83-91.
  • 7Blain EJ, Gilbeit SJ, Wardale RJ, et al . Up-regulation of matrix metalloproteinase expression and activation following cyclical compressive loading[J]. Arch Biochem Biophys, 2001, 396:49- 55.
  • 8Aaron RK, Boyan BD, Ciombor DM, et al. Stimulation of growth factor synthesis by electric and electromagnetic fields [J]. Clin Orthop, 2004, 419:30-37.
  • 9Cornell CN, Lane JM. Newest factors in fracture healing[J].Clin Orthop, 1992, 227 : 229.
  • 10Lee MS, Trindade MC, Ikenoue T, et al . Intermittent hydro static pressure inhibits shear stress induced nitric oxide release in human osteoarthritic chondroeytes in vitro[J]. J Rheumatol, 2003, 30:326-328

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