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支气管动脉灌注化疗加 ^(60)Co 外照射治疗晚期中心型肺癌 被引量:8

Bronchial Artery Infusion of Chemtherapeutic Agents plus 60 1Co External Irradiation in the Treatment of Advanced Central Lung Cancer
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摘要 为提高晚期中心型肺癌疗效,作者从1993年10月至1995年10月间,采用标准剂量,经支气管动脉灌注化疗2个周期,第二次动脉灌注化疗后48小时加60Co外照射方法,治疗不能手术切除的Ⅲ期非小细胞中心型肺癌30例,同时以单纯放疗30例作为对照组。结果表明近期疗效BAI+RT组优于RT组,1年生存率分别为76.67%和40.00%,P<0.05。对不能手术切除的Ⅲ期中心型肺癌,BAI+RT是一种效果较好的治疗方法,能明显提高近期疗效及1年生存率。 In order to improve curative effects of advanced central lung cancer, from October, 1993 to October, 1995, 30 patients with unresectable stage Ⅲ non small cell central lung cancer were treated with two cycles of standard dose of bronchial artery infusion (BAI) chemtherapy, plus 60 1Co external radiotherapy 48 hours after the second cycle of artery infusion chemothera py. Meanwhile, 30 comparable subjects trcated with radiotherapy (RT) alone were selected as the control group. Results showed that short term curative effects of BAI+RT were better than those of RT alone. One year survival tates were 76.67% and 40.00 %, respectively ( P <0.05). It is suggested that BAI+RT is an effective synthetical method of treatment for patients with unresectable stage Ⅲ central lung cancer. It may significantly improve short term curative effects and raise one year survival rates.
出处 《实用癌症杂志》 1997年第2期135-136,共2页 The Practical Journal of Cancer
关键词 动脉灌注 肺肿瘤 药物疗法 放射疗法 Lung cancer Artery infusion chemotherapy Radiochemotherapy
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