摘要
目的探讨广东地区大肠癌临床特点和变化趋势。方法总结分析广东五家医院1990年至2004年经病理确诊的大肠癌6501例资料。结果6501例大肠癌患者中位年龄59岁,好发年龄为61～70岁。青年大肠癌的比例从7.1%下降到3.5%。男:女为1.47:1,男性多于女性;随年龄增长。男女比例逐渐上升。于60岁左右达高峰后下降.呈一单峰曲线。在直肠癌与结肠癌比例为1.1:1,其中降结肠以上占27.6%,但随年龄增长和年份推移,直肠癌逐渐减少.而右半结肠癌逐渐增加。组织学分型以管状腺癌为主,占76.0%。住院患者Dukes分期多为中晚期.进展期癌(Dukes B、C、D期)共占93.9%。结论广东地区大肠癌发病高峰年龄已接近西方国家;青年大肠癌比例下降;男女比例随年龄增长呈先升后降趋势;直肠癌比例逐渐减少,右半结肠癌比例逐渐增加.发病部位右移提示应重视全结肠镜检查。
Objective To investigate the clinical characteristics of colorectal cancer and its trend in Guangdong province. Methods The data from 6501 patients with pathologically confirmed colorectal cancer of 5 hospitals from 1990 to 2004 was analyzed. Results The mean age of 6501 patients with colorectal cancer was 59 years old, with the predominant age ranged from 61 to 70 years old. The proportion of young patients decreased from 7. 1% to 3.5 %. and the ratio between male and female was 1.47 ： 1, which was gradually increased with increasing of age. The prevelence reached a high peak（60 years old） and dropped after that as a single peak curve. The ratio between rectal cancer and colon cancer was 1.1 ： 1, and the descending colon cancer accounted for 27. 6%. With ageing, the rectal cancers decreased while the right hemi colon cancer increased gradually. Tubular adenocarinoma was predominant with histological typing, which accounted for 76.0%. The progressing stage（Dukes B, C, and D） was found in 93.9% of all cases. Conclusions The onset age of patients with colorectal cancer become close to western country. The proportion of young patients are decreasing. The ratio between male and female displays a single peak curve from rising to dropping. A tendency of decreasing percentage in rectal cancer and the gradual increasing in right hemi colon cancer emphasize the importance of colonoscopy in colorectal caner screening.
出处
《中华消化杂志》
CAS
CSCD
北大核心
2007年第7期450-453,共4页
Chinese Journal of Digestion
关键词
结直肠肿瘤
种群特征
发生率
Colorectal neoplasms
Population characteristics
Incidence
