摘要
目的探讨血清视黄醇结合蛋白（RBP）、前白蛋白（Ph）在不同类型肝病诊断中的临床意义。方法用免疫比浊法检测117例不同类型肝病患者及86例正常人的血清RBP、PA水平，用溴甲酚绿法检测血清白蛋白（ALB），并对其中48例急性肝炎患者作动态观察。结果急性肝炎患者入院时血清RBP、PA明显下降，血清ALB下降不明显，治疗1个月后血清RBP、PA明显回升，而血清ALB明显下降；慢性肝炎患者血清RBP、PA、ALB偏低，与正常对照组比较无显著性差异；肝炎后肝硬化患者血清RBP、PA、ALB均下降。结论血清RBP、PA可作为反映急性肝损害的敏感指标，优于血清hLB，对肝病的诊断和预后判断有重要参考价值。
Objective To explore the value of combining detecting of serum RBP（Retinolbinding protein） and PA（Prealbumin） in diagnosis of different liver disease. Methods 117 cases of different liver diseases and 86 cases of healthy adults were detected the serum levels of RBP and PA with the method of Immunoturbidimetry and the levels of serum ALB（Albumin） with the method of Bromocresol green. 48 cases of acute hepatitis were observed dynamic. Results The acute hepatitis patients＇ serum levels of RBP and PA declined significantly and serum levels of ALB declined unconspicuously. After they were cured for a month, the serum levels of RBP and PA ascended distinctly. At the same time the serum levels of ALB declined visibly. The chronic hepatitis patients＇ serum levels of RBP, PA and ALB were little lower. There were no differences for the cases of healthy adults. The serum levels of RBP, PA and ALB of the hepatocirrhosis patients causing of hepatitis all declined. Conclusion The serum RBP and PA which are sensitive indexes reflecting liver damnification are better than serum ALB. It is valuable to measure the levels of RBP and PA in diagnosis and prognosis judgement of liver disease.
出处
《国际医药卫生导报》
2007年第15期127-128,126,共3页
International Medicine and Health Guidance News
