摘要
目的：探讨肝脏炎性假瘤的临床病理特征、诊断及鉴别诊断。方法：复习6例肝脏炎性假瘤患者的临床资料，并对其进行组织学观察和免疫组化标记。结果：6例标本中，男性5例，女性1例，年龄31～52岁，平均45岁。临床表现为右上腹胀痛。镜下病变组织为增生的胶原纤维，部分坏死组织周围绕以增生的纤维组织，见大量的浆细胞、淋巴细胞、单核细胞等炎细胞。免疫组化染色病变组织内淋巴细胞部分为CD20、CD45RA阳性；部分为CD3、CD45RO阳性；部分淋巴细胞轻链κ、轻链λ标记双项阳性。结论：肝脏炎性假瘤术前无法确诊，多以肝癌而手术，确诊只能依靠病理学，免疫组化标记可以起到辅助诊断的作用。治疗采用手术治疗、激素治疗，以及观察随访，预后良好。
Objective：To investigate the pathology, diagnosis and differential diagnosis of the inflammatory pseudotumor of the liver （IPL）. Methods： 6 cases of IPL were studied with hematoxylin and eosin （HE） staining and immunohistochemical EnVision - plus staining. 5 patients were male and 1 was female. The age was from 31 to 52. Results： The clinical features of IPL included right epigastric pains and gas pains at hepatic region. The hyperplastic collagen fibers with many lymphocytes, plasmocyte and mononuclear cells were found around the necrotic tissue. Conclusions： IPL is usually misdiagnosed as other tumors because it is uncommon. Pathological examination is the only mean to obtain the final diagnosis.
出处
《西北国防医学杂志》
CAS
2007年第4期273-274,共2页
Medical Journal of National Defending Forces in Northwest China
关键词
肝肿瘤
炎性假瘤
免疫组织化学
Inflammatory pseudotumor
Liver tumor
Immunohistochemistry
作者简介
钱震（1962-），男，副主任医师，Tel：0931—8975404
