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云南白药对比格犬牙龈炎的治疗作用 被引量:10

Therapeutic effects of Yunnan Baiyao on gingivitis in beagle dogs
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摘要 目的:评价云南白药对比格犬牙龈炎的治疗作用。方法:12只符合条件的比格犬随机分为云南白药组和空白对照组。2组动物分别用浸有1.23g/L云南白药溶液或生理盐水的棉球敷于牙龈治疗,1min/次,2次/d,持续14d。在给药前和末次给药后24h分别盲法对动物的菌斑(P),牙龈炎症状(G)和炎性浸润(INF)评分。结果:空白对照组动物的P、G、INF没有显著性差异(P>0.1),云南白药组动物的各评分指标均有显著性改善(P<0.05)。结论:云南白药可抑制比格犬牙龈炎菌斑形成,减轻牙龈炎症状和炎细胞的聚集。实验结果提示云南白药可能对临床牙龈炎有一定治疗作用。 Objective:To test the effects of Yunnan Baiyao on beagle dogs with gingivitis. Methods: 12 chosen beagle dogs were randomly distributed into two groups: control group and Yunnan Baiyao group. Normal saline (control group) or 1.23 g/L Yunnan Baiyao solution was applied on the dogs'teeth twice daily for 14 days. At day 0 and day 15, the scores for plaque (P), gingivitis (G) and inflammatory infiltrate (INF) were evaluated blindly. Results: P, G, and INF did not show any alteration in control group (P 〉0.1 ), while in Yunnan Baiyao group, there were significant reductions in all scores ( P 〈 0.05 ). Conclusion : Yunnan Baiyao inhibited plaque formation, abated existing gingivitis and inflammatory cells aggregation in beagle dogs. The present results suggested that Yunnan Baiyao may be a good option for the treatment of gingivitis.
出处 《实用口腔医学杂志》 CAS CSCD 北大核心 2007年第4期531-533,共3页 Journal of Practical Stomatology
关键词 云南白药 牙龈炎 菌斑 炎性浸润 牙周病 Yunnan Baiyao Gingivitis Plaque Inflammatory cell infiltration Periodontal disease
作者简介 通讯作者:杜俊蓉028-85503938 E-mail:dujr_l@163.com
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参考文献4

  • 1Page RC.The etiology and pathogenesis of periodontitis.Compend Contin Educ Dent,2002,23 (5 Suppl):11
  • 2蔡锡麟.云南白药的药理研究[J].中成药研究,1982,8:37-41.
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  • 4Tagge DL,O' Leary TJ,El-Kafrany AH.The clinical and histopathological response of periodontal pockets to root planning and oral hygiene.J Periodontol,1975,46(9):527

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