摘要
目的 探讨眼前段光学相干断层扫描仪（AC-OCT）检测前房深度（ACD）和晶状体厚度（LT）的一致性与可重复性。方法 对30例受试者（30只眼）的中央前房和晶状体，采用AC-OCT分别由测量者甲和乙，以及测量者甲在两个不同的时间点进行水平方向扫描；对其中的10例受试者（10只眼）的中央前房和晶状体水平方向扫描重复10次。采用类内相关系数（ICC）和变异系数（CV）作为评价测量的一致性，采用变异系数（CV）作为评价测量的可重复性。结果 ACD和LT的平均值分别为（3．16±0．27）mm和（3．90±0．26）mm。测量者间ACD和LT的ICC值分别为0．996（F=499．347，P=0．000）和0．996（F=539．069，P=0．000）；变异系数的平均值分别为0．47％±0．24％和0．37％±0．20％。测量者内ACD和LT的ICC值分别为0．999（F=2039．611，P=0．000）和0．999（F=1654．961，P=0．000）；变异系数的平均值分别为0．18％±0．22％和0．19％±0．16％。10例受试者（10只眼）的ACD及LIT扫描10次的变异系数平均值分别为0．39％±0．12％和0．30％±0．14％。结论 AC-OCT测量ACD和LT的一致性与可重复性较好，是一种精确可靠的测量ACD与LIT的工具。
Objective To assess the repeatability and reproducibility of anterior chamber depth （ACD）and lens thickness（LT）measured by Anterior Chamber-Optical Coherence Tomographer（AC-OCT）Methods Thirty eyes of 30 normal subjects were enrolled. ACD and LT were measured using AC-OCT by two ophthalmologists at the same time, and the one observer repeatedly measured ACD and LT in two different times. Ten eyes selected randomly from 30 normal subjects were measured ACD and LT in ten times by one observer. Reproducibility was made with intraclass correlation coefficient（ICC）and coefficient of variation（CV）, and repeatability was made with coefficient of variation. Results The mean of ACD and LT of 30 eyes were （3.16 ± 0.27） mm,and （3.90 ± 0.26） mm respectively. The ICC of interobservers of ACD and LT were 0.996 （F=499.347, P=0.000）and 0.996（F=539.069, P=0.000）, respectively. The mean of coefficient of variation of ACD and LT were 0.47%±0.24% and 0.37%± 0.20%,respectively. The ICC of ACD and LT in intraobservers were 0.999（F=2039.611, P=0.000）and 0.999（F=1654.961, P=0.000）,respectively. The mean of coefficient of variation of ACD and LT were 0.18% ± 0.22% and 0.19%± 0.16%, respectively. The mean of coefficient of variation of ACD and LT from 10 normal subjects who be measured 10 times were 0.39%± 0.12% and 0.30% ±0.14%, respectively. Conclusions ACD and LT are measured by AC-OCT with excellent repeatability and reproducibility. AC-OCT is a precise tool for evaluation of ACD and LT in the clinic.
出处
《中国实用眼科杂志》
CSCD
北大核心
2007年第6期600-603,共4页
Chinese Journal of Practical Ophthalmology
基金
广州市科技计划项目（2005J1-C0101）
关键词
眼前段光学相干断层扫描仪
前房深度
晶状体厚度
青光眼
Anterior Chamber-Optical Coherence Tomographer
Anterior champter depth
Lens thickness
Glaucoma
作者简介
通讯作者：刘杏，E-mail：liuxing@mail．sysu．edu．cn
