摘要
目的探讨新生儿换血治疗中使用血库血的铅暴露危险性。方法2006年6～12月对本院新生儿科37例因高胆红素血症进行换血治疗的新生儿进行换血前后血铅水平监测，并对换血使用的53份血库血进行血铅检测。血铅测定采用石墨炉原子吸收光谱法。结果53份血库血平均血铅水平为101．02μg／L，已处于铅中毒水平；而高血铅（≥100μg／L）的血库血占28．5％（15／53份），其中3份血库血样本血铅量≥200μg／L，达Ⅲ级铅中毒水平。高胆红素血症患儿换血后血铅值≥100μg／L的百分率由2．9％升高到19．0％，换血后平均血铅水平明显高于换血前（P〈0．01），血铅水平平均增加26．62μg／L，最高1例增加81．0μg／L。结论血库血铅污染明显，新生儿换血的血源存在血源性铅暴露的危险，应在采血前进行铅筛检，避免新生儿血源性铅中毒。
Objective To explore the danger of lead exposure in newborns who accepted the blood stored in blood bank for blood change treatment. Methods The lead level of blood was examined before and after blood change treatment for 37 neonates with hyperbilirubinemia who accepted 53 cases blood stored in blood bank during Jun. to Dec. 2006. The level of blood lead was measured by graphite stove atom absorb spectrum method. Results The average lead level of 53 cases blood stored in blood bank was 101.02 μg/L, which had attained the level of lead poisoning. There were 15 cases（28.5% ） whose blood lead levels was very high（≥ 100 μg/L） ,3 cases whose blood lead level ≥200 μg/L. After blood change treatment, the percentage of the blood lead level ≥ 100 μg/L rose from 2.9 % to 19.0 %. The average level of blood lead after blood change treatment was higher than before（ P 〈 0.01 ）. The average blood lead level of newborns increased 26.62 μg/L, and 1 newborn whose blood lead level increased 81.0 μg/L. Conclusions The lead pollution of blood stored in blood bank is very clear. It exists that the danger of lead exposure in neonatal blood change treatment. It is very important to have a lead screen before letting blood and avoid lead poisoning of blood source in newborns.
出处
《实用儿科临床杂志》
CAS
CSCD
北大核心
2007年第14期1057-1058,共2页
Journal of Applied Clinical Pediatrics
关键词
换血
婴儿
新生
血铅
血源性铅暴露
blood change treatment
infant, newborn
blood lead
lead exposure of blood source
作者简介
谢玲，女，主管检验师，研究方向为医学检验学。
