摘要
目的探讨中心静脉导管(CVC)的病原学特征。方法回顾分析近5年临床各科送检的CVC病原学结果及细菌耐药性。结果3189份CVC标本中471份(14.77%)检出致病菌514株,G+球菌、G-杆菌和真菌分别占42.41%、40.66%和16.93%;最常见的致病菌分别为表皮葡萄球菌(15.56%)、金黄色葡萄球菌(13.81%)、铜绿假单胞菌(13.23%)、肺炎克雷伯菌(7.59%)和鲍氏不动杆菌(6.23%);91.18%为耐甲氧西林金黄色葡萄球菌(MRSA),88.57%为耐甲氧西林凝固酶阴性葡萄球菌(MRCNS),12.00%肠杆菌科产超广谱β-内酰胺酶(ESBLs);44.12%铜绿假单胞菌和34.38%鲍氏不动杆菌全部耐药。结论CVC检出病原菌以耐药菌为主,应加强病原学监测及导管护理,是控制导管相关性感染的关键。
OBJECTIVE To investigate the characteristic of pathogens of central venous catheter（CVC）. METHODS The pathogens of CVC from different departments and their drug-resistances were analyzed retrospectively in recent 5 years. RESULTS Totally 471 （14. 77;） of 3 189 samples were isolated with 514 strains of microorganisms, of which G^＋ bacteria accounted for 42. 41;, G^- bacteria 40.66;, and yeasts 16. 93;. The most common pathogens were Staphylococcus epidermidis （ 15. 56;）, S. aureus （ 13. 81;）, Pseudomonas aeruglnosa （ 13. 23 ;）, Klebsiella pneumoniae （ 7. 59 ;） and Acinetobacter baumannii （ 6. 23; ）, respectively. 91.18; of S. aureus were MRSA, 88. 57; of S. epidermidls were MRCNS and 12; of Enterobacter were ESBLs. 44.12; of P. areuglnosa and 34.38; of A. baumannii were pan-drug resistant. CONCLUSIONS The most commonly encountered pathogens of CVC are almost drug-resistant, the organism monitoring and the medical attendance of catheters should be enforced.
出处
《中华医院感染学杂志》
CAS
CSCD
北大核心
2007年第7期819-821,共3页
Chinese Journal of Nosocomiology
关键词
中心静脉导管
病原菌
调查
Central venous catheter
Pathogen
Investigation
