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选择性海马杏仁核切除术治疗内侧型颞叶癫痫 被引量:1

Surgical treatment of mesial temporal lobe epilepsy by selective amygdalo-hippocampectomy via the modified Spencer's approach
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摘要 目的:颞叶内侧结构(杏仁核海马等)与颞叶癫痫的发生和传播密切相关。本文采用改良Spencer法选择性切除杏仁核海马,探讨在治疗内侧型颞叶癫痫的同时,尽可能保留颞叶新皮质的功能。方法:结合应用EEG、MRS、PETCT等检查结果对适合手术洽疗的200例内侧型颞叶癫痫病例的癫痫灶进行定位诊断,利用耳前直切口、三角形小骨片开颅,采用改良Spencer法,切除前颞叶颞下回2cm脑组织后进入侧脑室下角,显微镜下清晰显露杏仁核海马后酌情切除杏仁核、海马头部和体部。病理标本送常规检查。术后密切随访,观察近期疗效及长期随访结果。结果:200例中手术疗效满意173例。其中EngelⅠ级155例,Ⅱ级18例,Ⅲ级20例,Ⅳ级7例。病理标本提示170例(85%)存在明显海马硬化。术后无并发症发生。方法:改良Spencer法选择性切除杏仁核海马,对内侧型飘叶癫痫疗效满意,且较常规手术入路安全易行。 Objective: To discuss the Surgical treatment of mesial temporal lobe epilepsy by selective amygdalo - hippocampectomy via the modified Spencer' s approach. Method: Two hundred patients with intractable mesial temporal lobe epilepsy were identified with EEG. MRS. PETCT et. al., treated by selective amygdalo - hippocampectomy via the modified Spencer' s approach. The results of operation and follow - up were analysed.Results: As to seizure outcome, all patients were benefied from surgery. Surgical results were satisfactory in 173 patients (Engel Ⅰ in 155, Engel Ⅱ in 18 ) . There was no surgical complication. Condnsion: Operation is an effective way for the treatment of mesial temporal lobe epilepsy. Selective amygdalo- hippocampectomy via the modified Spencer' s approach is a safe and effective choice for mesial temporal lobe epilepsy.
出处 《福州总医院学报》 2007年第1期11-12,共2页 Journal of Fuzhou General Hospital
关键词 内侧型颞叶癫痫 选择性海马杏仁核切除术 改良Spencer法 Mesial temporal lobe epilepsy Selective amygdalo- hippocampectomy Modified Spencer' s approach
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参考文献5

  • 1Spencer DD,Inseroni J.Temporal lobectomy.In: Lueders H. eds[].Epilepsy.1991
  • 2Wieser HG.Selective amygdalohippocampectomy: indication, investigation, technique and results[].Advances and Technical Standards in Neurosurgery.1986
  • 3Wieser HG,Siegel AM,Yasargil MG.The Zurich amygdalo - hippocampectomy series: A short up - date[].Acta Neurochirurgica.1990
  • 4Wieser HG.Selective amygdalo - hippocampectomy: indications and follow-up[].Canadian Journal of Neurological Sciences.1991
  • 5Yasargil MG,Wieser HG,Valavanis A,et al.Surgery and results of selective amygdalo - hippocampectomyⅠone hundred patients with nonlesional limbic epilepsy[].Neurosurgery Clinics of North America.1993

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