摘要
目的探讨前列腺素E1脂微球载体制剂(LipoPGE1,凯时)和毫米波联合治疗糖尿病周围神经病变的效果。方法将98例糖尿病周围神经病变患者随机分3组,分别为常规治疗组(对照组),凯时组(第1组),凯时和毫米波联合治疗组(第2组),观察治疗前后自觉症状,腱反射和神经传导速度。结果第2组总有效率为91%显著高于对照组(P<0.01),第1组总有效率为69%,与对照组比较有显著差异(P<0.05)。第2组神经传导速度治疗后较治疗前显著改善(P<0.01),而且显著优于第1组(P<0.05)。结论凯时联合毫米波治疗糖尿病周围神经病变较单独应用凯时有效。
Objective To study the clinical effect of combined treatment of Lipo PGEl and millimeter wave on diabetic peripheral neuropathy. Methods 98 patients with diabetic peripheral neuropathy(DPN) were randomly divided into the first treatment group with Lipo - PGE1, and the second treatment group combined with Lipo PGEl and millimeter wave compared with the routin therapy group as control in order to observe the subjective symptom, tendon reflex and nerve conduction velocity, respectively. Results The total effective rates of the second treatment group was 91% , which was significantly higher than the control group ( P 〈 0.01 ) , and the total effective rates of the first treatment group was 69% , which was significantly different from the control group ( P 〈 0.05 ) , The nerve conduction velocity of the second treatment group was improved significantly after therapy(P 〈0.01 ) , which was better than that of the first treatment group(P 〈0.05). Conclusions Combined therapy of Lipo PGE1 and millimeter wave is more effective than treatment of Lipo PGEl alone for the treatment of DPN.
出处
《医学研究杂志》
2007年第7期114-116,共3页
Journal of Medical Research
关键词
凯时
毫米波
糖尿病周围神经病变
Lipo PGE1
Millimeter wave
Diabetic peripheral neuropathy