摘要
目的了解心血管疾病患者中高尿酸血症的发病情况,以及血尿酸水平与心血管疾病各相关因素之间的关系。方法连续入选2006年1～10月因心血管疾病住院的患者,测定血尿酸水平,分析患者高尿酸血症发病率,并从性别、年龄等方面进行对比。结果入选的722例40～89岁心血管疾病患者中,男性高尿酸血症患病率为32.27%(111/344)、女性为30.16%(114/378),高尿酸血症的相关危险因素有冠心病、高血压、糖尿病、高甘油三酯血症、血肌酐增高,在男性患者还有高胆固醇血症,女性患者还有年龄。高尿酸血症患者合并有3种及以上危险因素的比例明显高于无高尿酸血症者,男性为38.74%比22.75%,女性为45.61%比28.03%。结论心血管疾病患者中高尿酸血症发病率高,高尿酸血症患者的心血管疾病的危险因素具有聚集性,女性患者绝经前高尿酸血症发病率低于男性、绝经后与男性无明显差别,女性高尿酸血症发病率随年龄增长而上升。
Objective To study the attack instance of the hyperuricemia in patients with cardiovascular disease ,and the relation of uric acid level with cardiovascular risk factor. Methods The study was performed through consecutive survey.Patients with cardiovascular risk factors were enrolled from January 2006 to October 2006 consecutively.Snrem uric acid was measured and the incidence of hyperuricemia both in men and women were analyzed. Results 722 patients were enrolled （from 40 to 89 years old）. The prevalence of hyperuricemia was 32.27% in men and 30.16% in women. Hyperuricemia was positively correlated with coronary heart disease, hypertension,diabetes mellitus,hypertriglyceridemia,high level of serum creatinine both in men and women, and hypercholesterolemia separate in men, and age separate in women.The proportion of hyperuricemic patients with 3 or more risk factors is higher than that of non-hyperuricemic patients. Conclusion The prevalence of hyperuricemia in patients with cardiovascular risk factors is high. Cardiovascular risk factors of tencluster in hyperuricemia patients. The prevalence of hyperuricemia in postmenopausal women is as much as that in men. The prevalence of hypernricemia ascend along with age rose in women.
出处
《中国心血管病研究》
CAS
2007年第7期518-520,共3页
Chinese Journal of Cardiovascular Research
