摘要
目的了解东莞地区葡萄糖-6-磷酸脱氢酶(G6PD)缺乏症的发病情况。方法用G6PD/6PGD定量比值法对2399例新婚对象进行红细胞G6PD缺乏的临床检测。结果在2399例受检者中,G6PD缺乏者99例,发生率为4.13%(99/2399)。男性51例,占男性受检人数的4.57%(51/1117);女性48例,占女性受检人数的3.74%(48/1282)。结论东莞地区是G6PD缺乏症的高发区,应在全市各地普及推广G6PD的大人群筛查,尤其是育龄夫妇的筛查。
To find out the glucose - 6 - phosphate dehydrogenase deficiency incidence in Dongguan City . Methods : Blood samples from 2399 persons at reproduction - age were examined on G6PD/6PGD hematology by using G6PD/6PGD rate test. Results : There were 99 patients whose ratio of G6PD/6PGD were abnormal and incidence of G6PDdeficiency is 4. 13%. Among 99 patients, 51 persons were male, whose ratio is 4.57% ; 48 persons were female, whose ratio is 3.74%. Conclusion: There is a high incidence of G6PD deficiency in Dongguan City. It is necessarily to examine blood samples on G6PD deficiency among persons at reproduction - age.
出处
《中国优生与遗传杂志》
2007年第2期95-96,共2页
Chinese Journal of Birth Health & Heredity
关键词
G6PD缺乏症
育龄夫妇
发生率
G6PD deficiency
Persons at reproduction-age
Incidence