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原位肝移植的麻醉及围术期麻醉管理的探讨

Anesthesia for Orthotopic Liver Transplantation and Its Perioperative Management
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摘要 目的:探讨原位肝移植术的麻醉管理。方法:本组病人均采用全身麻醉,术中加强监测血流动力学、血气、血生化、凝血功能、血糖、体温、尿量。根据肝移植的无肝前期、无肝期、新肝期的特点给予相应的麻醉处理。结果:无肝期及新肝初期血流动力学波动较大,各期无严重的酸碱紊乱,电解质主要表现为低钙、凝血功能有一定紊乱,术中体温变化不明显,无肝期血糖升高,新肝期血糖逐渐下降。结论:肝移植麻醉中应维持血流动力学稳定,及时纠正水电解质、酸碱平衡的紊乱,加强血气、生化及凝血功能的检测与调控是手术麻醉成功的关键。 Objective:To investigate the perioperative changes and anesthetic management for patients under orthoptopic liver transplantation. Methods: General anesthesia Was conducted. Hemodynamics、blood gas、blood biochemistry、 coagulation function、 blood glucose、 body temperature、 urinary output were monitored duringthe operation. According to the characteristics of per-anhepatic phase, anhepatic phase and neohepatic phases. Corresponding anesthetic management measures were supplied. Results: Hemodynamics changes may occur greatly during anhepatic and early neohepaticphase. No marked acid - base disturbance occurred during orthotopic liver trabsplabtation. The main electrolytic change during perioperative phase was hypocalcemia. Disturbance of coagn- lation function to a certain degree occurred. The blood glucose level was higher than normal during pre - anhepatic phase, and gradually decreased during the neohepatic phase. There was not an marked change in body temperature. Conclusion: Attention should be paid to the anesthetic management and monctoring during different phase of orthotopic liver transplantation. Maintaining hemodynamics stability, correcting fluid electrolyte and acid - base disturbance in time, reinforcing the monitoring and adjustment of blood gas、biochemical alterations and coagulation function are the keys to successful operation.
作者 丁翠霞
出处 《内蒙古医学杂志》 2007年第5期547-549,共3页 Inner Mongolia Medical Journal
关键词 原位肝移植 麻醉 管理 Orthotopie liver transplantation Anesthesia Management
作者简介 丁翠霞(1966-),女,内蒙古扎兰屯市人,医学学士,副主任医师。
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参考文献6

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二级参考文献25

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