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肝细胞生长因子/c—met系统与头颈肿瘤 被引量:1

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摘要 肝细胞生长因子是一种多功能的细胞生长因子,其生物活性由c—met蛋白所介导,肝细胞生长因子通过与原癌基因c-met受体结合激活受体酪氨酸蛋白激酶活性调节细胞的分裂、增殖、分化、迁移等。故肝细胞生长因子/c—met信号传导在肿瘤的侵袭转移中发挥重要作用。人类许多肿瘤的生长、侵袭和转移与肝细胞生长因子/c—met系统密切相关。研究肝细胞生长因子/c-met系统与头颈部肿瘤侵袭、转移的关系,将对头颈肿瘤的诊断、治疗及预后有重要意义。
出处 《国际耳鼻咽喉头颈外科杂志》 2007年第3期162-165,共4页 International Journal of Otolaryngology-Head and Neck Surgery
作者简介 通信作者:黎万荣(Email:lwr0375@sina.com.cn)
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