摘要
目的观察和评价雾化吸入治疗儿童上呼吸道感染的疗效和安全性。方法将病毒性上呼吸道感染患儿155例,随机分为雾化1组52例、雾化2组53例和对照组50例,雾化1组用布地奈德和利巴韦林联合雾化治疗,雾化2组用利巴韦林雾化治疗,对照组口服利巴韦林片剂。结果治疗后三组间在发热、流涕症状的改善方面无统计学差异(p>0.05),而在咳嗽症状的改善方面有统计学差异(p<0.05),三组药物不良反应发生率有统计学差异(p<0.05)。结论布地奈德和利巴韦林联合雾化吸入治疗儿童上呼吸道感染可有效抑制病毒复制、减轻气道炎症反应,疗效确切,不良反应少,用药依从性高,值得临床推广应用。
Objective To evaluate the efficacy and safety of the treatment of aerosol inhalation for infection of upper respiratory tract in children. Method 155 children with viral upper respiratory tract infection were divided into three groups randomly. The children of the first inhalation group （ 52 cases ） were treated by inhalation of budesonide and ribavirin , the children of the second inhalation group （ 53 cases ） were treated by inhalation of ribavirin, the children of control group （ 50 cases ） were treated by ribavirin tablet. Result The symptom of cough was improved with significantly differences （ p 〈 0.05 ） and the symptoms of fever and snot were improved with no significantly differences （p 〉0.05 ） in three groups. The adverse reaction rates of three groups were 9.6%, 7.5% and 22%, with significantly differences （p 〈 0.05）. Conclusion Inhalation of budesonide and ribavirin could be effectively and safely used for treating infection of upper respiratory tract in children. It could inhibit the replication of vires actively and lessen the inflammation of respiratory tract with fewer side effects and high compliance. It was worthy to be popularized.
出处
《现代医院》
2007年第5期13-15,共3页
Modern Hospitals
关键词
雾化
上呼吸道感染
儿童
Aerosol inhalation, Infection of upper respiratory tract, Child
