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早期胃癌淋巴结转移影响因素的分析 被引量:11

Analysis of risk factors for lymph node metastasis in early gastric cancer
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摘要 目的探讨早期胃癌淋巴结的转移规律及其对预后的影响,为具有不同临床病理特征的早期胃癌患者选择合适的治疗方案。方法回顾性分析137例早期胃癌患者临床病理特征与淋巴结转移的关系,并分析早期胃癌术后5a生存率。结果肿瘤大小、浸润深度和组织学类型是影响早期胃癌淋巴结转移的独立危险因素,无淋巴结转移的早期胃癌术后5a生存率为93.2%,明显高于有淋巴结转移者的63.8%(P<0.05)。结论术前正确评估早期胃癌的淋巴结转移状态是选择合理治疗方案的重要条件。 Objective To explore the general pattern of lymph node metastasis and its effect on the prognosis in early gastric cancer, and to put forward suitable regimens for early gastric cancer with different clinicopathological characteristics, Methods The data of 137 patients with early gastric cancer were retrospectively analyzed with respect to the relationship between clinicopathological characteristics and lymph node metastasis, and the postoperative 5-year survival rate of early gastric cancer was analysed. Results The tumor size, depth of invasion and histological type were independent risk factors for lymph node metastasis in early gastric cancer. The postoperative 5-year survival rate of lymph node-negative patients (93. 2% ) was higher than that of lymph node-positive patients (63.8% , P 〈 0. 05). Conclusion Precise assessment of lymph node metastasis preoperatively is essential to the appropriate therapeutic options for early gastric cancer.
出处 《上海交通大学学报(医学版)》 CAS CSCD 北大核心 2007年第5期588-590,共3页 Journal of Shanghai Jiao tong University:Medical Science
关键词 胃肿瘤 淋巴结转移 多因素分析 gastric neoplasms lymph node metastasis multivariate analysis
作者简介 冯润华(1974-),男,上海人,主治医师,硕士;电子信箱:runhua_feng@yahoo.com.cn。 通讯作者:朱正纲,电子信箱:zzg1954@hotmail.com。
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参考文献10

  • 1Japanese Gastric Cancer Association.Japanese classification of gastric carcinoma-2nd english edition[J].Gastric Cancer,1998,1(1):10-24.
  • 2Lee HJ,Kim YH,Kim WH,et al.Clinicopathological analysis for recurrence of early gastric cancer[J].Jpn J Clin Oncol,2003,33 (5):209-214.
  • 3Roviello F,Rossi S,Marrelli D,et al.Number of lymph node metastases and its prognostic significance in early gastric cancer:a multicenter Italian study[J].J Surg Oncol,2006,94 (4):275-280.
  • 4Park IS,Lee YC,Kim WH,et al.Clinicopathologic characteristics of early gastric cancer in Korea[J].Yonsei Med J,2000,41 (5):607-614.
  • 5Folli S,Morgagni P,Roviello F,et al.Risk factors for lymph node metastases and their prognostic significance in early gastric cancer (EGC) for the italian research group for gastric cancer (IRGGC)[J].Jpn J Clin Oncol,2001,31 (10):495-499.
  • 6Onodera H,Tokunaga A,Yoshiyuki T,et al.Surgical outcome of 483 patients with early gastric cancer:prognosis,postoperative morbidity and mortality,and gastric remnant cancer[J].Hepatogas-troenterology,2004,51 (55):82-85.
  • 7Uedo N,Iishi H,Tatsuta M,et al.Longterm outcomes after en-doscopic mucosal resection for early gastric cancer[J].Gastric Cancer,2006,9 (2):88-92.
  • 8严超,朱正纲,诸琦,燕敏,陈军,刘炳亚,尹浩然,林言箴.内镜超声检查在早期胃癌术前分期的应用[J].中华肿瘤杂志,2003,25(4):390-393. 被引量:50
  • 9Hyung WJ,Cheong JH,Kim J,et al.Application of minimally invasive treatment for early gastric cancer[J].J Surg Oncol,2004,85 (4):181-185.
  • 10Yasuda K,Shiraishi N,Suematsu T,et al.Rate of detection of lymph node metastasis is correlated with the depth of submucosal invasion in early stage gastric carcinoma[J].Cancer,1999,85 (10):2119-2123.

二级参考文献14

  • 1Matsumoto Y, Yanai H, Tokiyama H, et al. Endoscopic ultrasonography for diagnosis of submucosal invasion in early gastric cancer. J Gastroenterol, 2000, 35: 326-331.
  • 2Shimizu S, Tada M, Kawai K. Endoscopic ultrasonography for early gastric cancer. Endoscopy, 1994, 26: 767-768.
  • 3Willis S, Truong S, Gribnitz S, et al. Endoscopic ultrasonography in the preoperative staging of gastric cancer: accuracy and impact on surgical therapy. Surg Endosc, 2000, 14: 951-954.
  • 4Kunisaki C, Shimada H, Nwnura M, et al. Appropriate lymph node dissection for early gastric cancer based on lymph node metastases.Surgery, 2001, 129: 153-157.
  • 5Shimada S, Yagi Y, Shiomori K, et al. Characterization of early gastric cancer and proposal of the optimal therapeutic strategy. Surgery, 2001,129: 714-719.
  • 6Yanai H, Noguchi T, Mizumachi S, et al. A blind comparison of the effectiveness of endoscopic ultrasonography and endoscopy in staging early gastric cancer. Gut, 1999, 44: 361-365.
  • 7Akahoshi K, Chijiiwa Y, Hamada S, et al. Ptetreatment staging of endoscopically early gastric cancer with a 15 MHz ultrasound catheter probe. Gastrointest Endosc, 1998, 48: 470-476.
  • 8Sano T, Kobori O, Muto T, et al. Lymph node metastasis from early gastric cancer: endoscopic resection of tumor. Br J Surg, 1992, 79:241-244.
  • 9Akahoshi K, Misawa T, Fujishima H, et al. Regional lymph node metastasis in gastric cancer: evaluation with endoscopic US. Radiology,1992, 182: 559-564.
  • 10Xiangming C, Hokita S, Natsugoe S, et al. Angiogenesis as an unfavorable factor related to lymph node metastasis in early gastric cancer. Ann Surg Oncol, 1998, 5: 585-589.

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