摘要
目的探讨中国17个汉族人群3个STR基因座的遗传关系。方法收集中国17个汉族人群D16S539、D7S820和D13S317基因座的基因频率资料,计算他们间的遗传距离,构建系统发生树。结果江苏、河南、太原、江西、安徽、台湾和深圳汉族聚为一大类,泉州、广东、福建、潮汕汉族为一类,荆州、成都、湖南、西安和贵州汉族为一类,而广西汉族单独为一类。结论研究结果与遗传学和民族学研究结果一致,并提示17个汉族人群STR基因频率分布与地理距离呈平行关系。
Objective To study the genetic relationship （3 short tandem repeat gene loci, abbreviated as 3 STR gene loci） in 17 groups of Han population in China. Methods Genetic data of D16S539, D7S820, and D138317 STR gene loci on 17 groups of Han population were collected, genetic distance was calculated and the Pylogenetic Tree chart was constructed based on the genetic distances among seventeen groups of Han population, A Neighbor- Joining method was used to draw the Pylogenetic Tree. Results Th e Pylogenetic Tree showed that the seven groups of Han population in Jiangsu, Henan, Taiyuan, Jiangxi, Anhui, Taiwan and Shenzhen cities or provinces were involved in an identical cluster; Quanzhou, Guangdong, Fujian, and Chaoshan in another, and Jingzhou, Chengdu, Hunan, Xi＇an and Guizhou in another, and Guangxi Han population in an unattached cluster. Conclusion The study results were in accordance with the researched outcomes of genetic and ethnology. This indicated that the STR gene frequency distribution in seventeen groups of Han population is parallel with the geographic distance.
出处
《右江民族医学院学报》
2007年第3期336-338,共3页
Journal of Youjiang Medical University for Nationalities
基金
贵州省教育厅科研基金(黔科教2005222)
黔南民族医专科研基金(QNYZ2005007)资助项目
关键词
STR
遗传距离
系统发生树
群体遗传学
汉族
中国
STR
genetic distance
phylogenetie tree
population genetics
Han population
China
