摘要
To describe a case of probable relapsing autoimmune hepatitis associated with vaccination against hepatitis A virus （HAV）. A case report and review of literature were written concerning autoimmune hepatitis in association with hepatitis A and other hepatotropic viruses. Soon a^er the administration of formalin-inactivated hepatitis A vaccine, a man who had recently recovered from an uncharacterized but self-limiting hepatitic illness, experienced a severe deterioration （AST 1687 U/L, INR 1.4）. Anti-nuclear antibodies were detectable, and liver biopsy was compatible with autoimmune hepatitis. The observation supports the role of HAV as a trigger of autoimmune hepatitis. Studies in helper T-cell activity and antibody expression against hepatic proteins in the context of hepatitis A infection are summarized, and the concept of molecular mimicry with regard to other forms of viral hepatitis and autoimmunity is briefly explored.
为了描述可能的复发的的自体免疫的肝炎的一个盒子，对肝炎与种痘联系了一个病毒(HAV ) 。文学的一份病案报告和评论与肝炎 A 和另外的亲肝病毒联合有关自体免疫的肝炎被写。此后不久使福尔马林失去活性的肝炎的管理一支疫苗，最近从 uncharacterized 恢复了的一个人但是自我限制的 hepatitic 病，经历了严重恶化(著名计算机生产厂商 1687 U/L， INR 1.4 ) 。反原子的抗体是可检测的，并且肝活体检视与自体免疫的肝炎兼容。观察作为自体免疫的肝炎的一个扳机支持 HAV 的角色。在肝炎的上下文对肝的蛋白质在助手 T 房间活动和抗体表示学习感染被总结，并且关于病毒的肝炎和汽车免疫的另外的形式的分子的模仿的概念是简短探索了。
作者简介
Correspondence to： Dr. PA Berry, Medway Maritime Hospital, 31 Penflow Street, Putney, London, SW 15 1LX, United Kingdom. philaberry@hotmail.com;Telephone： ＋44-798-5059279.
