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脑梗死后低钠血症与脑钠肽素的关系 被引量:4

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摘要 目的:探讨脑梗死患者血浆脑钠肽素(BNP)含量与低钠血症的关系,并探讨BNP与脑梗死病情轻重的关系。方法:用放射免疫检测法测定68例急性脑梗死患者24h(Ⅰ期)、72h(Ⅱ期)和>7d(Ⅲ期)血浆BNP含量。结果:大面积脑梗死组低钠血症血钠在Ⅱ期有显著下降(P<0.05),在Ⅲ期恢复正常,其血浆BNP含量在各期均升高,以Ⅱ期升高达最高峰(P<0.01)。小面积脑梗死组低钠血症未发生,血浆BNP的含量均在正常范围内。大面积脑梗死组与小面积脑梗死组相比,血浆BNP浓度有明显升高(P<0.01),差异有统计学意义。结论:血浆BNP与脑梗死后低钠血症的发生密切相关,且血浆BNP的浓度能够作为反映梗死病情轻重的指标之一。
出处 《实用医学杂志》 CAS 2007年第7期997-999,共3页 The Journal of Practical Medicine
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