摘要
为了解我国北方地区慢性湿疹患者斑贴试验结果及临床意义,回顾性分析了本地区近20年来积累的589例慢性湿疹患者斑贴试验结果,分析接触性变应原在不同性别、年龄、季节及年代的分布特征。结果斑贴试验阳性者269例,占45.7%。阳性率居前9位的接触性变应原分别为:20%松香5.9%(35例)、1%甲醛5.3%(31例)、1%次乙基二胺4.2%(25例)、30%羊毛醇4.1%(24例)、5%苯唑卡因3.6%(21例)、8%芳香混合物3.2%(19例)、5%硫酸镍2.7%(16例)、0.5%对苯二胺2.7%(16例)、3%卡巴混合物2.5%(15例)。接触变应原分布与性别、年龄、季节、发病年代等因素无关。说明慢性湿疹病人接触性变应原斑贴阳性率较高,外源性接触性变应原可能是慢性湿疹的重要致病因素。
To evaluate the results and clinical significance of patch testing in chronic eczema, 589 out-patients with chronic eczema were patch tested during the last 20 years. It was found that 45.7% (269/589) patients with chronic eczema had positive reactions to the 20 allergens tested. Among them, positive rates were 20% colophony 5.9% (35/589), 1%fonnaldehyde 5.3% (31/ 589), 1%ethenyldiamine4.2% (25/589), 30%lanonol 4.1% (24/589), 5% benzecain 3.6% (21/589), 8% fragrance mix 3.2% (19/589) , 5%nickel sulfate 2.7% (16/589), 0.5%paraphenylenediamine 2.7% (16/589) and 3% earba mix 2.5% (15/589). There was no correlation between distribution of contact allergens and factors including gender, age, season or onset era. It indicated that the positive rate of contact allergens is high. Contact allergens may take part in the pathogensis of chronic eczema.
出处
《中国工业医学杂志》
CAS
北大核心
2007年第2期102-104,共3页
Chinese Journal of Industrial Medicine
基金
教育部新世纪优秀人才支持计划资助(NCEP-04-0287)
关键词
慢性湿疹
斑贴试验
变应原
Chronic eczema
Patch testing
Allergen
作者简介
赵丽萍(1971-),女,博士研究生,现工作单位:沈阳军区总医院皮肤科。
通讯作者。