摘要
光学相干层析成像（OCT）是一种非接触、无创的新型层析成像技术，它利用弱相干光反射测量技术，对体内生物组织结构进行高分辨率层析成像．笔者利用基于共焦模式的OCT蒙特卡罗仿真模型研究了在OCT系统中高散射生物组织背向散射光的漫反射率，指出满足相干条件的背向散射光强是样品臂入射光强的10^-8～10^-10，具体CCD探测器阵列的分析显示OCT系统高速成像的关键在于提高光电探测阵列的响应灵敏度．如果要实现一定分辨率的视频成像，响应灵敏度必须大于4200V／（μ·cm^-2），这是当前光电探测阵列所无法实现的．
Optical coherence tomography （OCT） is a non-contact, non-invasive tomography ,which uses optical low coherence reflectometry to obtain the cross-section image of living biological tissue with high resolution. An OCT Monte-Carlo simulation model based on confocal mode is used to study the efficiency of back-scattering light from tissue in OCT system. The simulation result indicates that the intensity of useful back-scattering light for OCT imaging is about 10^-8 - 10^-10 times that of incident light. Analysis of some specific CCD detector arrays shows that high-speed OCT depends on the responsivity of photo detector array. To realize video rate OCT system with determinate resolution, the responsivity of photo detector array should be greater than 4 200 V/ （μJ·cm^-2） , which is now unavailable in most commercial products.
出处
《天津大学学报》
EI
CAS
CSCD
北大核心
2007年第1期94-97,共4页
Journal of Tianjin University(Science and Technology)
关键词
光学相干层析成像
光电探测阵列
背向散射光
蒙特卡罗仿真
optical coherence tomography
photo detector array
back-scattering light
Monte-Carlo simulation
作者简介
李刚（1959-），博士，教授，ligang59@tju．edu．cn．
