摘要
目的了解乳腺癌患者相关症状的发生情况及其对生活质量的影响。方法横断面调查设计,以记忆症状评估量表和生活质量调查问卷(第3版)对四川大学华西医院等3所医院的200例乳腺癌患者进行面对面的问卷调查。结果乳腺癌各种症状中发生率居前五位的有缺乏活力、脱发、精神紧张、出汗和焦虑不安;出现频率高居前五位的症状是缺乏活力、睡眠不好、口干、没有食欲和出汗;严重程度居前五位的症状是脱发、缺乏活力、睡眠不好、精神紧张和进食口味改变;对患者造成困扰程度居前五位的症状是脱发、感到“我看起来不像自己”、睡眠不好、没有食欲和缺乏活力;对乳腺癌患者整体生活质量的影响从大到小依次为缺乏活力、焦虑不安、疼痛、睡眠不好、便秘、急躁易怒、口干、出汗、手脚感到麻木或刺痛、皮肤改变、腹泻、恶心、没有食欲、气紧或呼吸困难,确定系数R2=0.790。结论乳腺癌患者最突出的症状是缺乏活力;脱发是使患者感到最困扰的问题;其他值得注意的症状有:感到“我看起来不像自己”,睡眠不好,没有食欲。对患者整体生活质量评分产生影响的症状有14项,它们可以共同解释乳腺癌患者整体生活质量评分总变异的79.0%。
Objective To identify the correlative symptoms of breast cancer patients and their influence on quality of life. Methods The cross-sectional study was used. A face-to-face survey was administered to 200 breast cancer patients, using two scales： （1） Memorial Symptom Assessment Scale（MSA）; （2） European Organization for Research and Treatment of Cancer Core Quality-of-Life Questionnaire （Version 3） [EORTIC QLQ-C30]. Results The top five most highly prevalent symptoms were： lack of energy, hair loss, nervousness, sweating and worry. The five most frequent symptoms were： lack of energy, difficulty in sleeping, dry mouth, lack of appetite and sweating. The five most severe symptoms were： hair loss, lack of energy, difficulty in sleeping, nervousness and a change in food preference. The top fivesymptoms causing much distress were： hair loss, a feeling of＇I don＇t look like myself＇, difficulty in sleeping, lack of appetite and lack of energy. The major factors influencing quality of life were： lack of energy, worry, pain, difficulty in sleeping, constipation, irritability, dry mouth, sweating, numbness/tingling in hands/feet, changes in skin, diarrhea, nausea, lack of appetite, and shortness of breath. Adjusted R square was 0.790. Conclusions The most conspicuous symptom in breast cancer patients is lack of energy. The symptom that distresses patients most is hair loss. The other notable symptoms are： ＂I don＇t look like myself＇, difficulty in sleeping, and lack of appetite. In addition, the quality of life is influenced by fourteen symptoms, and these symptoms account for 79.0% of the variance in quality of life.
出处
《中国循证医学杂志》
CSCD
2007年第3期169-174,共6页
Chinese Journal of Evidence-based Medicine
关键词
乳腺癌
相关症状
生活质量
Breast cancer
Correlative symptoms
Quality of life
作者简介
马玲，女（1981年～），在读硕士研究生，以护理教育为主要研究方向。
通讯作者Email：spjane514@163．com
