摘要
目的:探讨C-反应蛋白(CRP)与系统性红斑狼疮(SLE)的相关性。方法:测定90例SLE患者身高、体重、血压等一般情况及血清CRP、高密度脂蛋白(HDL),计算体质量指数(BMI)、平均动脉压(MAP)和SLE活动指数评分(SLEDAI),分析CRP与SLE病情活动性及其他指标的相关性。结果:CRP与SLEDAI之间无明显相关(P>0.05),而与BM(IP<0.05)和MAP(P<0.05)之间呈正相关,与HDL(P<0.05)呈负相关。结论:CRP与SLE的病情活动无相关,与SLE患者心血管危险因素相关。
Objective： To investigate the correlation between C-reactive protein （CRP） and systemic lupus erythematosus （SLE）. Methods： In 90 patients with SLE,the general information including height,weight,and blood pressure was collected,and the levels of serum CRP and high-deusity lipoprotein were measured. The body mass index,mean arterial pressure,and SLE disease activity index （SLEDAI） were calculated. The correlation of the serum CRP level to SLE disease activity and other indexes was analyzed. Results：No correlation was found between serum CRP level and SLEDAI. The serum CRP level was positively correlated with body mass index and mean arterial pressure,and negatively correlated with high-density lipoprotein level （all P 〈 0.05）. Conclusion：CRP is correlated with the risk of cardiovascular disease, not SLE disease activity.
出处
《中国医科大学学报》
CAS
CSCD
北大核心
2007年第1期88-89,共2页
Journal of China Medical University
关键词
C-反应蛋白
系统性红斑狼疮
C-reactive protein
systemic lupus erythematosus
作者简介
夏丽萍（1977-），女，医师，硕士E—mail：syxialiping505@sohu．com
