摘要
目的研究急性颅脑损伤与全身炎症反应综合征（SIRS）发生的关系及对预后的影响。方法回顾性分析310急性颅脑损伤患者，根据SIRS诊断标准，研究SIRS发生与病情轻重、预后的关系，SIRS组再根据诊断标准项目符合数分组，分别比较各组病例的病死率。结果急性颅脑损伤后SIRS的发生率为61．0％，与性别、年龄无关，与GCS评分有一定关系，GCS评分越高，SIRS发生率越低；SIRS组的病死率显著高于非SIRS组（P〈0．05），且病死率随着SIRS严重程度增加而增高（P〈0．05）。结论急性颅脑损伤常合并SIRS，SIRS的发生与预后有关，应结合是否发生SIRS来综合判断急性颅脑损伤的轻重，SIRS的发生及严重程度可作为急性颅脑损伤预后判断及治疗指导的指标。
Objective To study the relationship between the systemic inflammatory response syndrome （SIRS） and acute eraniocerebral injury, and to discuss the prognosis of SIRS patients. Method Three hundred and ten patients with acute eraniocerebral injury were analyzed retrospectively. According to the tempomture, heart rates, respiratory rates and count of white blood cell, the relationship between severity of diesease and SIRS, SIRS and prognosis were studied. Patients with SIRS were divided into three groups, the mortality rate was compared in every group. Results Among the 310 patients 61.0% were accompanied with SIRS. The occurrence of SIRS had no relationship with sex and age, and had some relationship with GCS scale. The occurrence rote of SIRS was higher associated with the lower of GCS scale. The mortality rate of SIRS patients was highly than that in control group. Moreover, the mortality rate was raised with the severity SIRS. Conclusions Acute eraniocerebral injury was usually complicated by SIRS. The occurrence of SIRS after brain injury produced clinical worsening and a poor outcome. It should combine occurrence of SIRS in judging the severity of acute eraniocerebral injury. The occurrence and severity of SIRS could serve as indexes in guiding treatment and judging outcome.
出处
《中华急诊医学杂志》
CAS
CSCD
2007年第2期147-150,共4页
Chinese Journal of Emergency Medicine
关键词
颅脑损伤
全身炎症反应综合征
预后
Craniocerebral injury
Systemic inflammatory response syndrome
Prognosis
