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某厂锻压车间恶性肿瘤高发原因调查

THE INVESTIGATION OF THE CAUSE OF HIGH INCIDENCE RATE OF MALIGNANT TUMOR IN THE FRONT LINE WORKERS IN SMITHING WORKSHOP
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摘要 [目的]调查某厂锻压车间生产一线职工恶性肿瘤高发的原因。[方法]通过问卷调查和面谈的方法,了解职工有无可导致肿瘤的烟酒嗜好和特殊饮食习惯;并对车间生产环境空气进行检测,了解是否存在导致人体肿瘤发生的有害因素,并与同为热加工车间的炼钢车间生产一线职工肿瘤发生率进行对比。[结果]锻压车间生产一线职工肿瘤发生率高于炼钢车间生产一线职工,两车间职工肿瘤发生率差异明显(χ2=30.77,P﹤0.05);锻压车间生产环境空气中氯仿、四氯化碳、铅、锰等含量均低于国家卫生标准,而苯并芘含量大大超过前苏联标准。[结论]锻压车间生产一线职工肿瘤高发原因与生产环境空气中苯并芘含量关系密切,应通过改革热处理方法,彻底消除苯并芘对人体的危害,以保障生产一线职工健康。 [ Objective] To investigate the cause of high incidence rate of malignant tumor in the front line workers in smithing workshop. [ Methods] Questionnaire survey and interview wore conducted to study whether cigarette and alcohol addiction or special diet existed in workers which may result in cancer; air in the workshop was also monitored to know whether there was risk factors for cancer. Comparison was conducted between the workers in steel-maklng workshop and the workers in snithing workshop about the incidence rate of malignant tumor. [ Results] The incidence rate of malignant tumor in the front line workers was higher than workers in steel-making workshop. There was statistically significant difference of the incidence rate between workers in two workshops (x^2 = 30.77, P 〈 0.05), the contents of chloroform, tetrachloride, lead, manganese, etc in air wore lower than the national standards, but the BaP content was much higher than the Soviet Russia standards. [ Conclusions] The cause of high incidence rate of malign tumor in the front line workers in smithing workshop is closely related to the BaP content in workshop. The heat treatment methods should be reformed to eliminate the harm to workers drastically, and ensure the health of front line workers.
作者 朱光云
出处 《现代预防医学》 CAS 北大核心 2007年第3期560-561,571,共3页 Modern Preventive Medicine
关键词 肿瘤 苯并芘 Tumor BaP
作者简介 朱光云(1955-),男,本科,副主任技师,研究方向:人事管理
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  • 1徐谦,杨进波,蒋长征,杨杪,柯磊,何美安,王峰,邬堂春.热休克蛋白70的表达在苯并[a]芘致DNA损伤中的作用[J].中华劳动卫生职业病杂志,2004,22(2):96-99. 被引量:8
  • 2柯磊,徐谦,杨进波,杨杪,谭皓,邬堂春.苯并(a)芘作用下的A549细胞株热休克蛋白70家族多态性表达[J].中华劳动卫生职业病杂志,2004,22(5):375-378. 被引量:3
  • 3沈靖,叶本法,徐耀初,沈洪兵,陈建国,张宝初,柳标,姜允辉,李文广,姚红玉,詹重厚,赵新民.烟、酒、茶等因素与肝癌关系的流行病学研究[J].中国慢性病预防与控制,1994,2(4):150-152. 被引量:8
  • 4赵宁,俞顺章,孙伟明.原发性肝癌危险因素的广义相对危险度模型分析[J].中华肿瘤杂志,1994,16(5):331-336. 被引量:10
  • 5翁心植.控制吸烟是防治呼吸疾病的首要举措[J].心肺血管病杂志,1997,16(3):234-234.
  • 6Talaska G, Jaeger M, Reilman R, et al. Chronic, topical exposure to benzo [a]pyrene induces relatively high steady-state levels of DNA adducts in target tissues and alters kinetics of adduct loss. Genetics, 1996,93:7789-7793.
  • 7Fitzgerald DJ, Robinson NI, Pester BA. Application of benzo (a) pyrene and coal tar tumor dose-response data to a modified benchmark dose method of guideline development. Environ Health Perspect, 2004, 112:1341-1346.
  • 8Suzui M, Masuda M, Lim JT, et al. Growth inhibition of human hepatoma cells by acyclic retinoid is associated with induction of p21CIP1 and inhibition of expression of cyclin Df. Cancer Res, 2002,62: 3997-4006.
  • 9Wakino S, Kintscher U, Kim S, et al. Retinoids inhibit proliferation of human coronary smooth muscle cells by modulating cell cycle regulators. Arterioscler Thromb Vasc Biol,2001,21:746-751.
  • 10James SY, Lin F, Kolluri SK, et al. Regulation of retinoic acid receptor beta expression by peroxisome proliferator-activated receptor gamma ligands in cancer cells. Cancer Res, 2003,63:3531-3538.

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