摘要
[目的]对前列佳胶囊干预前列腺增生症患者的效果进行评价。[方法]采用随机平行对照试验方法,选择102例前列腺增生症(BPH)患者,随机分为干预组(54例)和对照组(48例),干预组患者服用前列佳胶囊,对照组患者服用安慰剂,疗程12周。[结果]干预后患者国际前列腺症状评分(IPSS)、最大尿流率(MFR)、生活质量评分(QOL)及夜尿次数与干预前比较,均有明显改善(P均<0.01)。干预前后对比,两组患者的前列腺体积均有缩小(P<0.01)。干预后,干预组最大尿流率上升,对照组则下降,差异有统计学意义(P<0.01)。前列佳胶囊改善最大尿流率的作用,主要表现在中、轻度前列腺增生症患者,而对于重度前列腺增生症患者的影响不明显。[结论]前列佳胶囊在改善患者排尿困难症状、减少夜尿次数和提高尿流率等方面有肯定的效果。
[ Objective] To determine the effect of ProstataTM on benign prostatic hyperplasia （ BPH ）. [ Methods] 102 man over the age of 49 years who had benign prostatic hyperplasia were randomly assigned in this double - blind randomized controlled trials. The patients in the intervention group were given orally ProstataTM, 2 softgels daily for 12 weeks, while the patients in the control group were given placebo for same duration. [ Results] Their primary outcome parameters, including international prostate symptom score（IPSS）, quality of life（ QOL）, maximum urinary flow rate（MFR） and night urine were significantly improved （P 〈0.01 ） compared with that in pretreatment in the intervention group. The results showed that there was a significant difference in maximum urinary flow rate between the intervention and control group, especially for mild and moderate BPH But, there was no significant difference in maximum urinary flow rate in severe BPH between the intervention and control group. After 12 weeks of therapy, the mean volume of prostate was decreased significantly compared with pretreatment beth in the intervention and control group. [ Condusion] The results suggest that Prostata plex improvessymptoms and objective measures of benign prostatic hyperplasia.
出处
《上海预防医学》
CAS
2007年第2期49-52,共4页
Shanghai Journal of Preventive Medicine
关键词
前列佳胶囊
前列腺增生症
干预试验
Prostata plex
Benign prostatic hyperplasia
Intervention trial
作者简介
施榕（1961-），男，教授，硕士。
