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半肝血流完全阻断无血肝切除术的临床研究 被引量:20

Study of bloodless hepatectomy under occlusion of total hemihepatic vessel
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摘要 目的探讨半肝血流完全阻断下无血肝切除术的临床意义。方法对两组各14例原发性肝癌患者分别施行半肝血流完全阻断无血肝切除术(A 组)和全肝入肝血流阻断肝切除术(B组),比较两组患者术中肝血流阻断时间、术中出血量、肝切除体积、术后肝功能恢复情况、并发症发生率等指标。结果两组在肝血流阻断时间和肝切除体积无显著差异的条件下,A 组的术中出血量平均为(296±240)ml,B 组平均为(582+497)ml,两组比较差异有统计学意义(P<0.05)。术后第1、3、7天血清前白蛋白水平 A 组为(164±39)mg/L、(111±17)mg/L 和(104±23)mg/L,显著高于 B组的(134±34)mg/L、(90±22)mg/L 和(82±35)mg/L(P<0.05),两组其他观察指标差异无统计学意义(P>0.05)。结论半肝血流完全阻断无血肝切除术能显著减少肝切除术中出血量及肝功能损害。 Objective To explore the preliminary clinical evaluation of hepatectomy with total hemihepatic vascular exclusion. Methods Twenty-eight patients with primary liver cancer were divided into two groups of hepatectomy with total hemihepatie vascular exclusion (group A) and total hepatic inflow occlusion (group B). The time of hepatic vascular control, intraoperative blood loss, volume of removed liver, postoperative liver function recovery and complications were compared between the two groups. Results The intranperative blood loss in group A was (296 ±240) ml, which was less significantly than that in group B[ (582 ±497) ml] (P〈0. 05). The serum pre-albumin levels on the day 1,3 and 7 after operation in group A were ( 164 ± 39) mg/L, ( 111 ± 17 ) mg/L and ( 104 ± 23 ) mg/L, which were higher significantly than that in group B[ ( 134 ±34) mg/L, (90 ±22) mg/L and(82 ±35) mg/L] (P 〈0. 05). While the time of hepatic vascular control and volume of lost liver were no difference between the groups(P 〉0. 05). There were no significant difference in other items between the groups. Conclusions Intraoperative blood loss and liver damage of hepatectomy under the total hemihepatie vascular exclusion could be less than that under the other methods of vascular occlusion. It could be worth improving and applying further.
出处 《中华外科杂志》 CAS CSCD 北大核心 2007年第3期186-188,共3页 Chinese Journal of Surgery
关键词 肝切除术 肝细胞癌 肝功能试验 Hepatectomy Carcinoma,hepatocellular Liver function tests
作者简介 通讯作者:杨甲梅,Email:lilytongy@hotmail.com
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参考文献3

  • 1Torzilli G,Makuuchi M,Ioue K.The vascular control in liver resection:revisitation of a controversial issue.Hepatogast roenterology.2002,49:28-31.
  • 2吴孟超.肝脏手术//吴孟超.肝脏外科学.2版.上海:上海科学技术文献出版社,2000:550.
  • 3Swank GM,Deitch EA.Role of the gut in multiple organ failure:bacterial translocation and permeability changes.World J Surg,1996,20:411-417.

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