摘要
目的评价综合方案治疗急性甲醇中毒视功能损害的疗效。方法对27例（54只眼）急性甲醇中毒患者采用皮质激素、扩张血管、活血化瘀、改善微循环、钙离子拮抗剂、微量元素、大量B族维生素、神经营养、高压氧等综合治疗方案，进行前后对照并随访一个月，观察视力、视野及图形视觉诱发电位（P-VEP）、眼底血管的改变。结果治疗后有1例（2眼）视力从无光感增进至0．06、0．09，6例（12眼）视力从光感、指数增进达≥0．1，16例（32眼）视力提高2行或以上；14例（28眼）视力≥1．0。15只眼治疗前P-VEP100波熄灭，治疗后9只眼重新出现，经统计，P值〈0．05有显著性差异。治疗后视力、视野及P-VEP有效为96％，显效1视力93％、视野91．6％、P-VEP86％，总显效率为93．6％。结论综合治疗方案对抢救保持和恢复急性甲醇中毒患者的视功能具有显著疗效。
Objective To value the integrating remedies for the visual function injuries caused by the acute methanol poisoning. Methods The total of 27 patients were compared between pre-remedy and postremedy over one month including the cortical hormone, vasldilator, stasis release, microcirculation improvement, calcium antagonist, trace elements, Vitamin B＇s, neurotonic, and hyperbaric oxygenation by visual acuity, automated threshold perimertry, Pattern-visual evoked potential （Pattem-VEP）,and change of fundus vessels. Resuits 1 patient （2 eyes） with no visual sensitivity improved by 0.06-0.09.6 patients （12 eyes） with visual sensitivity only improved by over 0.1 in index.16 patients （32 eyes） improved on visual acuity by upper 2 lines; 14 patients （28 eyes） improved by better than 1.0 visual acuity. 9 eyes recovered the P100 fluctuation of Patternvisual evoked potential （Pattern-VEP） out of 15 eyes.p〈0.05.Total effective rate of visual acuity,visual field, and Pattem-VEP is 96% of efficency; visual acuity 96%,visual field 91.6%, and P-VEP 86%,causing 93.6% of total efficient rate. Conclution the integrating remedies are of efficient to visual function recovery in the acute methanol poisoning.
出处
《中国实用眼科杂志》
CSCD
北大核心
2007年第1期118-121,共4页
Chinese Journal of Practical Ophthalmology
基金
广东省自然科学基金资助,项目号（5001768）
关键词
甲醇
中毒
视功能
综合治疗
眼底血管
methanol
poisoning
visual function
integrating remedies
funds vessels.potential
作者简介
通讯作者
