摘要
胰岛素抵抗（IR）是近年来研究的热点，越来越多的证据表明IR具有显著的性别差异，且女性发生IR的危险性似乎较男性更高。IR的性别差异与脂肪分布、性激素、性别相关的基因表达、血浆游离脂肪酸以及对治疗的反应等多方面因素相关，其发生机制尚不明确，可能主要由性别相关的基因表达及相应代谢调控所决定。
Insulin resistance is one of the hot topics in recent years. Numerous evidences suggest that females are more likely to have insulin resistance than males. Gender differences of insulin resistance are related to fat disposition, sex hormones, genes and their expression, free fatty acids in plasm and the response to treatments. The mechanism is not clear yet. Probablely it might be decided by gene expression and corresponding metabolic control.
出处
《国际内分泌代谢杂志》
2007年第1期13-15,共3页
International Journal of Endocrinology and Metabolism
关键词
胰岛素抵抗
糖尿病
性别
Insulin resistance
Diabetes
Gender
