摘要
目的:利用肝癌周期性筛检资料,确定筛检间隔。方法:嵌套病例对照研究。结果:经一次AFP阴性筛检,OR值下降为基准的10%左右;连续两次阴性和连续三次阴性其OR值相差不大;一次阴性筛检后,其OR值迅速下降,随着时间推移,其保护效应逐渐减少,1.5a左右保护效益基本消失。
Objective :To try to determine the periodic screening interval for liver cancer.Method :The nested casecontrol studies were used.Result :After a negative screening test,the OR declines to about one tenth as before.The OR value after two continuous negative screening tests is similar to that after three continuous negative tests.On TSLT,the results show that the risk for liver cancer drops after a negative test.As time elapsed,the OR rises gradually,and its protective effect against liver cancer will disappear after 1.5a.Conclusion :It is suggested that the appropriate screening interval for high risk population of liver cancer be a year.
出处
《南京铁道医学院学报》
1996年第4期226-228,共3页
Journal of Nanjing Railway Medical College
基金
国家自然科学基金
关键词
筛检间隔
LOGISTIC回归
肝癌
nested casecontrol study
screen study
logistic model
liver cancer